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340.654.01 Epidemiology and Natural History of Human Viral Infections


3rd term
6 credits
Academic Year:
2017 - 2018
East Baltimore
Class Times:
  • M W F,  1:30 - 3:20pm
Auditors Allowed:
Yes, with instructor consent
Grading Restriction:
Letter Grade or Pass/Fail
Homay Farzadegan
Course Instructor:

General biology and introductory epidemiology.


Emphasizes biology, epidemiology and pathogenesis of diseases caused by human viruses. Discusses virus interaction with host, diagnostic methodologies, immunization and treatment of viral infections. Examines relationships between oncogenesis and viral infections, such as Hepatitis/liver cancer, HPV/cervical cancer, EBV/Burkitt’s lymphoma and HTLV/leukemia. Covers the biology and natural history of major viral families (such as retroviruses, rabies, and others). Also covers Prion diseases, which are similar to, but not viral infections.

Learning Objectives:

Upon successfully completing this course, students will be able to:

  1. Describe the common structures and functions of viruses and their components, including genetics.
  2. Identify the main steps of viral pathogenesis
  3. Discuss virus-host interactions
  4. Recognize the advantages and limiting factors related to antiviral treatment options
  5. List several viruses and describe the processes by which they can cause cancer
  6. Recall the interaction between viral agents and other factors in the disease pathway
  7. Compare the pathogenesis of retroviruses with other viruses, including the mechanisms of invasion and integration and synthesis of new viral particles
  8. Recognize and describe the issues of treatment, prevention, and future concerns of human immunodeficiency virus and AIDS
  9. Compare and contrast the epidemiology and natural history of other human viral pathogens, including influenza, herpes simplex virus, bovine spongiform encephalitis and others
Methods of Assessment:

Mid-term exam 25%, Final exam 25%, Presentation and Discussion 25%, and Attendance and Participation 25%.

Instructor Consent:

No consent required

Special Comments:

Content similar to 260.623-624