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Course Catalog

340.620.01 Principles of Clinical Epidemiology

Department:
Epidemiology
Term:
2nd term
Credits:
2 credits
Academic Year:
2017 - 2018
Location:
East Baltimore
Class Times:
Course will begin at 8 AM - 10:20 AM
  • Tuesday,  8:00 - 10:20am
Auditors Allowed:
Yes, with instructor consent
Grading Restriction:
Letter Grade or Pass/Fail
Contact:
Kunihiro Matsushita
Course Instructors:
Resources:
Prerequisite:

340.751 (Epidemiologic Methods 1)

Description:

Presents lectures and interactive sessions designed to expose students to basic principles of clinical epidemiology and introduce key methods utilized in clinical outcomes research. Focuses on principles and methods in clinical epidemiology which would be most utilized by clinicians/clinician researchers for screening and diagnosis of illness as well as for prognostication and decision-making. Incorporates principles and methods related to measurement of relevant patient outcomes such as patient preferences and patient reported outcomes. Introduces methods and issues in studying clinical epidemiology in health care settings (e.g. administrative data).

Learning Objectives:

Upon successfully completing this course, students will be able to:

  1. Describe how epidemiological methods are applied to medicine and how scientific evidence drive decision on clinical practice.
  2. Draw a ROC curve to understand and estimate the effect and implications of different cutoff points in diagnostic test
  3. Evaluate the performance of diagnostic tests taking into account characteristics of the test (sensitivity, specificity, etc.), potential outcomes and the features of the population (prevalence of disease and risk factors)
  4. Describe key factors for deciding optimal outcome measures for a clinical study
  5. Describe advantages and disadvantages of clinical trials and observational studies for evaluating treatment effects
  6. Build a decision analysis tree based on probabilities and see how different outcomes influence the decision making in clinical settings
Methods of Assessment:

Homework assignments 56% (14% each), final project 24%, debate preparation & quality 10%, class attendance and participation 10%

Instructor Consent:

No consent required