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Course Catalog

340.674.11 Causal Inference: Emulating a Target Trial Using Observational Data

Cancelled

Department:
Epidemiology
Term:
Summer Inst. term
Credits:
2 credits
Academic Year:
2017 - 2018
Location:
East Baltimore
Dates:
Wed 06/14/2017 - Thu 06/15/2017
Class Times:
  • W Th,  9:00am - 5:00pm
Auditors Allowed:
No
Grading Restriction:
Pass/Fail
Contact:
Frances Burman
Resources:
Description:

Learn how to determine “what works” using data from observational and randomized studies

Introduces students to a general framework for the assessment of comparative effectiveness and safety research. The framework, which can be applied to both observational data and randomized trials with imperfect adherence to the protocol, relies on the specification of a (hypothetical) target trial. Explores key challenges for comparative effectiveness research and critically reviews methods proposed to overcome those challenges. The methods are presented in the context of several case studies for cancer, cardiovascular, renal, and infectious diseases.

Learning Objectives:

Upon successfully completing this course, students will be able to:

  1. Formulate sufficiently well-defined causal questions for comparative effectiveness research
  2. Specify the protocol of the target trial
  3. Design analyses of observational data that emulate the protocol of the target trial
  4. Critique observational studies and randomized for comparative effectiveness research
Methods of Assessment:

Critique of a clinical trial protocol 100%

Instructor Consent:

No consent required