120.861.01
Special Topics in Biochemistry: X-Ray Crystallography-A Hands on Workshop
Location
East Baltimore
Term
Summer Term
Department
Biochemistry and Molecular Biology
Credit(s)
3
Academic Year
2017 - 2018
Instruction Method
TBD
Auditors Allowed
Yes, with instructor consent
Available to Undergraduate
No
Grading Restriction
Letter Grade or Pass/Fail
Course Instructor(s)
Course Instructor(s)
Juergen Bosch
Contact Name
Frequency Schedule
Every Year
Resources
Prerequisite
Some basic knowledge of UNIX or Linux is desirable.
Enables students to carry out all key steps to successfully solve and refine a protein crystal structure. Theoretical aspects are followed by application to various problem sets. Topics include tricks for data collection, data processing and collection. Touches upon all standard techniques such as molecular replacement, SAD phasing and MAD phasing, both in theory and then applied in practical context with previously collected data. Identification of unknown ligand densities and model refinement lead to the last part of preparing publication quality figures using PyMol.
Learning Objectives
Upon successfully completing this course, students will be able to:
- Process and analyze x-ray data from protein crystals.
Enrollment Restriction
None
Students can visit http://lupo/jhsph.edu/boschlab/Xray_Workshop.html for updated information about the course.