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Course Catalog

120.606.01 Cellular Stress in Physiology and Disease

Biochemistry and Molecular Biology
4th term
3 credits
Academic Year:
2016 - 2017
East Baltimore
Class Times:
  • Tu Th,  10:30 - 11:50am
Auditors Allowed:
Yes, with instructor consent
Grading Restriction:
Letter Grade or Pass/Fail
Jiou Wang
Course Instructors:

Students should have a background of undergraduate or graduate level coursework in Molecular Biology.


Examines stress sensing and response pathways at the DNA, RNA, and protein levels, covering transcriptional regulation, RNA processing, and protein quality control. Also discusses Organelle-specific stress responses at the level of the endoplasmic reticulum and mitochondria are also discussed. Disseminates course material through formal lectures and discussions of literature. Local JHU scientists highlight each topic by presenting ongoing laboratory research, a “meet the expert” opportunity.

Learning Objectives:

Upon successfully completing this course, students will be able to:

  1. Describe the basics for how cells sense and respond to a wide variety of cellular stress agents and maintain fitness and survival through quality control
  2. Understand the basis for state-of-the-art laboratory approaches to research the molecular and cellular biology of stress and quality control
  3. Gain an appreciation of cutting edge research conducted at JHU on cellular stress and quality control
Methods of Assessment:

This course is evaluated as follows: 40% mid-term exam, 50% final exam and 10% class participation.

Instructor Consent:

Consent required for all students

Consent Note:

Contact instructor for consent.

For consent, contact: