260.711.01 Principles of Neuroimmunology
- Molecular Microbiology and Immunology
- 4th term
- 3 credits
- Academic Year:
- 2014 - 2015
- East Baltimore
- Class Times:
- Tu Th, 9:00 - 10:20am
Basic knowledge of brain anatomy, physiology and biology.
Briefly covers the role of specific cells of the central nervous system (CNS), immune functions of CNS cells, and trafficking of leukocytes into the CNS, both in health and disease. Subsequently, it discusses various immune cells, e.g. monocytes, T cells, B cells, inflammatory molecules like cytokines, chemokines, metalloproteinases, and prostaglandins in more detain focusing on their role in either protecting from neurological disease or in causing CNS disease pathologies, including cognitive dysfunction. Presentations from experts in the field address topics such as multiple sclerosis, the role of the Blood Brain Barrier in neurological disease, autism, HIV and other neurotropic microbes.
- Learning Objectives:
- Explain how the immune system and cellular brain components contribute to neurological disease
- Describe the types and effector functions of resident and peripheral immune cells in the human brain, in health and disease
- Methods of Assessment:
Course participation and a final exam.
- Enrollment Restriction:
Basic knowledge of biology
- Instructor Consent:
No consent required