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Course Catalog

260.605.01 Genomics


Molecular Microbiology and Immunology
2nd term
4 credits
Academic Year:
2014 - 2015
East Baltimore
Class Times:
  • M W F,  10:30 - 11:50am
Auditors Allowed:
Yes, with instructor consent
Grading Restriction:
Letter Grade or Pass/Fail
Jonathan Pevsner
Course Instructor:
  • Jonathan Pevsner

Explores genomes across the tree of life, using the tools of bioinformatics. Topics include viruses; bacteria and archaea; protozoa (e.g. Plasmodium); plants (with a focus on Arabidopsis and rice); the fungi; the metazoans (Drosophila, C. elegans, the rodents, the primates, and human). Each lecture highlights features of the relevant genome(s), key websites and bioinformatics tools, the phylogenetic context in which to understand the significance of the organism, and genomics-based approaches to human disease. Weekly computer labs introduce students to genomics software available on the internet, including tools for genome annotation, comparison, and analysis.

Learning Objectives:

Upon successfully completing this course, students will be able to:

  1. Define the main features of viral, prokaryotic, and eukaryotic genomes
  2. Define the relevance of various genomes to human disease
  3. Use web-based tools for genome analysis (e.g. annotation and comparison)
  4. Read papers on the sequencing of the human genomes and other genomes, and evaluate the quality and limitations of the analytic approaches
Methods of Assessment:

One midterm exam; one final exam; weekly quizzes.

Instructor Consent:

No consent required

Jointly Offered With: