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260.711.01 Principles of Neuroimmunology

Molecular Microbiology and Immunology
4th term
3 credits
Academic Year:
2013 - 2014
East Baltimore
Class Times:
  • Tu Th,  9:00 - 10:20am
Auditors Allowed:
Yes, with instructor consent
Grading Restriction:
Letter Grade or Pass/Fail
Monique Stins
Course Instructor:
Frequency Schedule:
Every Other Year
Next Offered:
2018 - 2019

Basic knowledge of brain anatomy, physiology and biology.


Covers the origin of specific cells of the central nervous system, immune functions of CNS cells, and trafficking of leukocytes into the CNS with mention of relevant anatomy (blood, brain, barrier, etc). Discusses monocytes, T cells, B cells, cytokines, chemokines, metalloproteinases, and prostaglandins. Explores how these mediators contribute to development, plasticity and pathology of the CNS. Presentations address multiple sclerosis, Creutzfeld and Jacob disease, HIV dementia and Alzheimer’s disease.

Learning Objectives:

Upon successfully completing this course, students will be able to:

  1. Explain how the immune system and cellular brain components contribute to neurological disease
  2. Describe the types and effector functions of resident and peripheral immune cells in the human brain, in health and disease
Methods of Assessment:

Course participation and a final exam.

Enrollment Restriction:

Basic knowledge of biology

Instructor Consent:

No consent required