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Course Catalog

340.754.01 Methodologic Challenges in Epidemiologic Research

4th term
5 credits
Academic Year:
2013 - 2014
East Baltimore
Class Times:
  • M W F,  8:30 - 9:50am
Auditors Allowed:
Grading Restriction:
Letter Grade or Pass/Fail
Ayesha Khan
Course Instructors:

Epidemiologic Methods 1-3 (340.751340.753) and either Statistical Methods in Public Health I-III (140.621140.623) or Methods in Biostatistics I-III (140.651140.653).


Integrates and extends material learned in the three-course Epidemiologic Methods sequence. Focuses on the application of strategies for addressing key methodologic challenges that arise when carrying out epidemiologic research. Incorporates experiential learning components, including computer-based laboratory exercises and a practicum, which require working knowledge of SAS or STATA.

Learning Objectives:

Upon successfully completing this course, students will be able to:

  1. Identify complex methodological problems in epidemiologic research, such as (a) missing data, (b) information bias, (c) confounding bias, (d) selection bias, (e) multiple exposures, and (f) multilevel determinants of disease, and state implications for et
  2. Apply appropriate analytic tool(s) (e.g., multiple imputation, propensity scores, inverse probability weighting, regression calibration, and multilevel models) to diagnose and account for complex methodological problems, such as those listed above
  3. Evaluate the sensitivity of an etiologic inference to possible bias due to complex methodological problems, such as those listed above
Methods of Assessment:

40% multiple-choice or short answer examination, 40% practicum (e.g., brief scholarly paper or poster), 20% participation in lectures and laboratories.

Enrollment Restriction:

No auditors permitted.

Instructor Consent:

Consent required for some students

Consent Note:

Consent required for special students and non-JHSPH students.

For consent, contact: