260.711.01 Principles of Neuroimmunology
- Molecular Microbiology and Immunology
- 1st term
- 3 credits
- Academic Year:
- 2013 - 2014
- East Baltimore
- Class Times:
- Tu Th, 9:00 - 10:20am
Basic knowledge of brain anatomy, physiology and biology.
Covers the origin of specific cells of the central nervous system, immune functions of CNS cells, and trafficking of leukocytes into the CNS with mention of relevant anatomy (blood, brain, barrier, etc). Discusses monocytes, T cells, B cells, cytokines, chemokines, metalloproteinases, and prostaglandins. Explores how these mediators contribute to development, plasticity and pathology of the CNS. Presentations address multiple sclerosis, Creutzfeld and Jacob disease, HIV dementia and Alzheimer’s disease.
- Learning Objectives:
- Explain how the immune system and cellular brain components contribute to neurological disease
- Describe the types and effector functions of resident and peripheral immune cells in the human brain, in health and disease
- Methods of Assessment:
Course participation and a final exam.
- Enrollment Restriction:
Basic knowledge of biology
- Instructor Consent:
No consent required