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Course Catalog

260.655.01 Protein Bioinformatics and Structure

Molecular Microbiology and Immunology
4th term
3 credits
Academic Year:
2012 - 2013
East Baltimore
Class Times:
  • Tu Th,  3:30 - 4:50pm
Auditors Allowed:
Yes, with instructor consent
Grading Restriction:
Letter Grade or Pass/Fail
Sean Prigge
Course Instructors:
Frequency Schedule:
Every Other Year
Next Offered:
2019 - 2020

Introduction to Molecular Biology (120.602) or consent of instructor


Provides students with an overview of protein bioinformatics including computational and experimental approaches. Introduces amino acid and protein physical properties as well as the alignment and evolution of protein sequences. Presents protein structure and methods of structure determination as well as the use of protein databases and software for visualizing proteins and generating publication quality figures. Discusses methods for secondary and tertiary protein structure prediction including homology modeling. Also covers methods for modeling small/molecule-protein interactions within the context of rational drug discovery and design. Finally, introduces students to experimental and computational aspects of mapping protein interaction networks.

Methods of Assessment:

4 homework assignments and final exam

Instructor Consent:

No consent required

Jointly Offered With:
Special Comments:

Three Friday computer labs will provide students with practical experience with web-based tools.