340.670.11
Genetic Epidemiology in Populations
Location
East Baltimore
Term
Summer Institute
Department
Epidemiology
Credit(s)
2
Academic Year
2012 - 2013
Instruction Method
TBD
Start Date
Monday, June 18, 2012
End Date
Friday, June 22, 2012
M, Tu, W, Th, F, 8:30am - 12:00pm
Auditors Allowed
No
Available to Undergraduate
No
Grading Restriction
Letter Grade or Pass/Fail
Course Instructor(s)
Contact Name
Frequency Schedule
Every Year
Resources
Prerequisite
Basic knowledge of epidemiology and biostatistics
This course will cover designs and methods for genetic epidemiology studies of unrelated individuals. Several population genetics concepts relevant to understanding genetic epidemiology designs and statistical tools will be introduced including concepts of quantitative and qualitative traits, genetic risk models, allele/haplotype frequency estimation, and migration/admixture. Methods for the evaluation of single and multiple genetic loci in the context of direct and indirect (linkage disequilbrium) associations with human disease will then be addressed, with examples from both genome-wide and candidate gene approaches. Methods for gene-gene and gene-environment interaction assessment will also be presented. The lecture material will be supplemented with examples using public and simulated data and currently available free software.