Welch Center Core Faculty Member Lawrence J. Appel, MD, MPH, presented the main results from the OmniHeart Randomized Trial at a late-breaking clinical trials session at the American Heart Association’s Scientific Sessions on November 15, 2005.
According to Dr. Appel, lead author of the National Institutes of Health-funded OmniHeart Trial and Hopkins professor of Medicine, substituting protein or monounsaturated fats for 10 percent of dietary carbohydrates in a healthy diet can take a bite out of heart disease risk. “Both the general public and the scientific research community are extremely interested in the health effects of shifting calories from carbohydrates," he said. "Our study provides evidence that substituting carbohydrates with protein (about half from plants) or with unsaturated fat (mostly monounsaturated fat) can lower blood pressure, improve cholesterol levels, and reduce heart disease risk.”
The study, which was funded by the National Heart, Lung,and Blood Institute, and conducted at the Johns Hopkins Medical Institutions and the Brigham and Women’s Hospital, is being simultanously published the November 16 issue of the Journal of the American Medical Association. Click here for the abstract, and here to read the full article.