Skip Navigation

Banner

Rakai Health
Sciences Program

Chronology

Structure

Current Research

NIH International Center for Excellence in Research

Publications

Community Services

 

Publications

Rakai Programs Recent Publications:

Gray RR,Tatem AJ,Lamers S,Hou W,Laeyendecker O,Serwadda D,Serwankambo N,Gray RH,Wawer M,Quinn TC,Goodenow MM,Salemi M. Spatial phylodynamics of HIV-1 epidemic emergence in east Africa. AIDS.2009 Jul 29. [Epub ahead of print]

Wawer MJ, Makumbi F, Kigozi G, Serwadda D, Watya S, Nalugoda F, Buwembo D, Ssempijja V, Kiwanuka N, Moulton LH, Sewankambo NK, Reynolds SJ, Quinn TC, Opendi P, Iga B, Ridzon R, Laeyendecker O, Gray RH. Circumcision in HIV-infected men and its effect on HIV transmission to female partners in Rakai, Uganda: a randomised controlled trial. Lancet. 2009 Jul 18;374(9685):229-37.

Johnson KE, Sherman ME, Ssempiija V, Tobian AA, Zenilman JM, Duggan MA, Kigozi G, Serwadda D, Wawer MJ, Quinn TC, Rabkin CS, Gray RH. Foreskin inflammation is associated with HIV and herpes simplex virus type-2 infections in Rakai, Uganda. AIDS. 2009 Jul 3. [Epub ahead of print]

Mehta SD, Gray RH, Auvert B, Moses S, Kigozi G, Taljaard D, Puren A, Agot K, Serwadda D, Parker CB, Wawer MJ, Bailey RC. Does sex in the early period after circumcision increase HIV-seroconversion risk? Pooled analysis of adult male circumcision clinical trials. AIDS. 2009 Jul 31;23(12):1557-64.

Nalugoda F, Wagman J, Kiddugavu M, Kiwanuka N, Garrett E, Gray RH, Serwadda D, Wawer MJ, Emanuel EJ. Is there coercion or undue inducement to participate in health research in developing countries? An example from Rakai, Uganda. J Clin Ethics. 2009 Summer;20(2):141-9.

Gray RH. Methodologies for evaluating HIV prevention intervention (populations and epidemiologic settings). Curr Opin HIV AIDS. 2009 Jul;4(4):274-8. Review.

Kigozi G, Lukabwe I, Kagaayi J, Wawer MJ, Nantume B, Kigozi G, Nalugoda F, Kiwanuka N, Wabwire-Mangen F, Serwadda D, Ridzon R, Buwembo D, Nabukenya D, Watya S, Lutalo T, Nkale J, Gray RH. Sexual satisfaction of women partners of circumcised men in a randomized trial of male circumcision in Rakai, Uganda. BJU Int. 2009 Jun 12. PMID: 19522862

Gray RH. Infectious disease: Male circumcision for preventing HPV infection. Nat Rev Urol. 2009 Jun;6(6):298-9. PMID: 19498404

Reynolds SJ, Nakigozi G, Newell K, Ndyanabo A, Galiwongo R, Boaz I, Quinn TC, Gray R, Wawer M, Serwadda D. Failure of immunologic criteria to appropriately identify antiretroviral treatment failure in Uganda. AIDS. 2009 Mar 27;23(6):697-700.

Tobian AA, Ssempijja V, Kigozi G, Oliver AE, Serwadda D, Makumbi F, Nalugoda FK, Iga B, Reynolds SJ, Wawer MJ, Quinn TC, Gray RH. Incident HIV and herpes simplex virus type 2 infection among men in Rakai, Uganda. AIDS. 2009 May 25. PMID: 19474649

Kiggundu V, Watya S, Kigozi G, Serwadda D, Nalugoda F, Buwembo D, Settuba A, Anyokorit M, Nkale J, Kighoma N, Ssempijja V, Wawer M, Gray RH. The number of procedures required to achieve optimal competency with male circumcision: findings from a randomized trial in Rakai, Uganda. BJU Int. 2009 Apr 17. PMID: 19389002

Redd AD, Dabitao D, Bream JH, Charvat B, Laeyendecker O, Kiwanuka N, Lutalo T, Kigozi G, Tobian AA, Gamiel J, Neal JD, Oliver AE, Margolick JB, Sewankambo N, Reynolds SJ, Wawer MJ, Serwadda D, Gray RH, Quinn TC. Microbial translocation, the innate cytokine response, and HIV-1 disease progression in Africa. Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6718-23.

Eshleman SH, Laeyendecker O, Parkin N, Huang W, Chappey C, Paquet AC, Serwadda D, Reynolds SJ, Kiwanuka N, Quinn TC, Gray R, Wawer M. Antiretroviral drug susceptibility among drug-naive adults with recent HIV infection in Rakai, Uganda. AIDS. 2009 Apr 27;27(7):845-52. PMCID: PMC2676205

Suntoke TR, Hardick A, Tobian AA, Mpoza B, Laeyendecker O, Serwadda D, Opendi P, Gaydos CA, Gray RH, Wawer MJ, Quinn TC, Reynolds SJ. Evaluation of multiplex real-time PCR for detection of Haemophilus ducreyi, Treponema pallidum, herpes simplex virus type 1 and 2 in the diagnosis of genital ulcer disease in the Rakai District, Uganda. Sex Transm Infect. 2009 Apr;85(2):97-101. Epub 2008 Dec 9. PMCID: PMC2692240

Ruark A, Shelton JD, Halperin DT, Wawer MJ, Gray RH. Universal voluntary HIV testing and immediate antiretroviral therapy. Lancet. 2009 Mar 28;373(9669):1078; author reply 1080-1. No abstract available. PMID: 19328994

Tobian AA, Serwadda D, Quinn TC, Kigozi G, Gravitt PE, Laeyendecker O, Charvat B, Ssempijja V, Riedesel M, Oliver AE, Nowak RG, Moulton LH, Chen MZ, Reynolds SJ, Wawer MJ, Gray RH. Male circumcision for the prevention of HSV-2 and HPV infections and syphilis. N Engl J Med. 2009 Mar 26;360(13):1298-309. PMCID: PMC2676895

Tobian AA, Charvat B, Ssempijja V, Kigozi G, Serwadda D, Makumbi F, Iga B, Laeyendecker O, Riedesel M, Oliver A, Chen MZ, Reynolds SJ, Wawer MJ, Gray RH, Quinn TC. Factors Associated with the Prevalence and Incidence of Herpes Simplex Virus Type 2 Infection among Men in Rakai, Uganda. J Infect Dis. 2009 Feb 16. MS 105526

Polis CB, Lutalo T, Wawer M, Serwadda D, Kigozi G, Nalugoda F, Kiwanuka N, Gray R. Int J Gynaecol Obstet. Coerced sexual debut and lifetime abortion attempts among women in Rakai, Uganda. 2009 Feb;104(2):105-9.

Sagar M, Laeyendecker O, Lee S, Gamiel J, Wawer MJ, Gray RH, Serwadda D, Sewankambo NK, Shepherd JC, Toma J, Huang W, Quinn TC. Selection of HIV variants with signature genotypic characteristics during heterosexual transmission. J Infect Dis. 2009 Feb 15;199(4):580-9. PMID: 19143562

Gray RH, Wawer MJ, Serwadda D, Kigozi G. The role of male circumcision in the prevention of human papillomavirus and HIV infection. J Infect Dis. 2009 Jan 1;199(1):1-3. No abstract available. PMID: 19086812

Kigozi G, Gray RH, Wawer MJ, Serwadda D, Makumbi F, Watya S, Nalugoda F, Kiwanuka N, Moulton LH, Chen MZ, Sewankambo NK, Wabwire-Mangen F, Bacon MC, Ridzon R, Opendi P, Sempijja V, Settuba A, Buwembo D, Kiggundu V, Anyokorit M, Nkale J, Kighoma N, Charvat B. The Safety of Adult Male Circumcision in HIV-Infected and Uninfected Men in Rakai, Uganda. PLoS Med. 2008 Jun 3;5(6):e116.

Godfrey Kigozi, Stephen Watya, Chelsea B. Polis, Denis Buwembo, Valerian Kiggundu, Maria J. Wawer, David Serwadda, Fred Nalugoda, Noah Kiwanuka, Melanie C. Bacon, Victor Ssempijja, Frederick Makumbi and Ronald H. Gray. The effect of male circumcision on sexual satisfaction and function, results from a randomized trial of male circumcision for human immunodeficiency virus prevention, Rakai, Uganda BJU International. 101, 1, 2008, 65-70.

Grady C, Wagman J, Ssekubugu R, Wawer MJ, Serwadda D, Kiddugavu M, Nalugoda F, Gray RH, Wendler D, Dong Q, Dixon DO, Townsend B, Wahl E, Emanuel EJ. Research benefits for hypothetical HIV vaccine trials: The views of Ugandans in the Rakai District. IRB. 2008 Mar-Apr;30(2):1-7.

Brahmbhatt H, Sullivan D, Kigozi G, Askin F, Wabwire-Mangenm F, Serwadda D, Sewankambo N, Wawer M, Gray R. Association of HIV and Malaria With Mother-to-Child Transmission, Birth Outcomes, and Child Mortality. J Acquir Immune Defic Syndr. 2008 Apr 1;47(4):472-476.

Gray RH, Wawer MJ, Kigozi G, Serwadda D. Commentary: Disease modelling to inform policy on male circumcision for HIV prevention. Int J Epidemiol. 2008 May 9. [Epub ahead of print].

Gray RH, Wawer MJ, Polis CB, Kigozi G, Serwadda D. Male Circumcision and Prevention of HIV and Sexually Transmitted Infections. Curr Infect Dis Rep. 2008 May;10(2):121-7.

Chang LW, Kagaayi J, Nakigozi G, Galiwango R, Mulamba J, Ludigo J, Ruwangula A, Gray RH, Quinn TC, Bollinger RC, Reynolds SJ. Telecommunications and Health Care: An HIV/AIDS Warmline for Communication and Consultation in Rakai, Uganda. J Int Assoc Physicians AIDS Care (Chic Ill). 2008 Sep;7(3):130-2. Epub 2008 Apr 25.

Kiwanuka N, Laeyendecker O, Robb M, Kigozi G, Arroyo M, McCutchan F, Eller LA, Eller M, Makumbi F, Birx D, Wabwire-Mangen F, Serwadda D, Sewankambo NK, Quinn TC, Wawer M, Gray R. Effect of Human Immunodeficiency Virus Type 1 (HIV-1) Subtype on Disease Progression in Persons from Rakai, Uganda, with Incident HIV-1 Infection. J Infect Dis. 2008 Feb 11.

Gamiel JL, Tobian AA, Laeyendecker OB, Reynolds SJ, Morrow RA, Serwadda D, Gray RH, Quinn TC. Improved Performance of Enzyme-Linked Immunosorbent Assays and the Effect of HIV Co-Infection on the Serologic Detection of Herpes Simplex Virus Type-2 in Rakai, Uganda. Clin Vaccine Immunol. 2008 Mar 5.

Chang LW, Kagaayi J, Nakigozi G, Packer AH, Serwadda D, Quinn TC, Gray RH, Bollinger RC, Reynolds SJ. Responding to the Human Resource Crisis: Peer Health Workers, Mobile Phones, and HIV Care in Rakai, Uganda. AIDS Patient Care STDS. 2008 Feb 21.

Safaeian M, Kiddugavu M, Gravitt PE, Gange SJ, Ssekasanvu J, Murokora D, Sklar M, Serwadda D, Wawer MJ, Shah KV, Gray R. Determinants of incidence and clearance of high-risk human papillomavirus infections in rural Rakai, Uganda. Cancer Epidemiol Biomarkers Prev. 2008 Jun; 17(6): 1300-7.

Safaeian M, Kiduggavu M, Gravitt PE, Gange SJ, Ssekasanvu J, Murokora D, Sklar M, Serwada D, Wawer MJ, Shah KV, Gray R. Prevalence and risk factors for carcinogenic human papillomavirus infections in rural Rakai, Uganda. Sex Transm Infect. 2008 Jun 11. [Epub ahead of print]

Wagman J, Baumgartner JN, Geary CW, Nakyanjo N, Ddaaki WG, Serwadda D, Gray R, Nalugoda FK, Wawer MJ. Experiences of Sexual Coercion Among Adolescent Women: Qualitative Findings From Rakai District, Uganda. J Interpers Violence. 2008 Dec 24.

Kagaayi J, Gray RH, Brahmbhatt H, Kigozi G, Nalugoda F, Wabwire-Mangen F, Serwadda D, Sewankambo N, Ddungu V, Ssebagala D, Sekasanvu J, Kigozi G, Makumbi F, Kiwanuka N, Lutalo T, Reynolds SJ, Wawer MJ. Survival of infants born to HIV-positive mothers, by feeding modality, in Rakai, Uganda. PLoS One. 2008;3(12):e3877. Epub 2008 Dec 9. PMCID: PMC2588542

Gray, Ronald H, Serwadda D, Kigozi G, Wawer, Maria J. Male Circumcision and HIV Prevention. HIV Prevention - A Comprehensive Approach. Ed. Kenneth H. Mayer and H.F. Pizer. 2008.146-166.

Gray RH, Kigozi G, Serwadda D, Makumbi F, Nalugoda F, Watya S, Moulton L, Chen MZ, Sewankambo NK, Kiwanuka N, Sempijja V, Lutalo T, Kagayii J, Wabwire-Mangen F, Ridzon R, Bacon M, Wawer MJ. The effects of male circumcision on female partners' genital tract symptoms and vaginal infections in a randomized trial in Rakai, Uganda. Am J Obstet Gynecol. 2008 Oct 29.

Gray RH, Wawer MJ. Control of sexually transmitted infections for HIV prevention - Authors' reply. Lancet. 2008 Oct 11; 372(9646):1297-1298.

Gray RH, Wawer MJ. Reassessing the hypothesis on STI control for HIV prevention. Lancet. 2008 Jun 21; 371(9630):2064-5.

Zablotska IB, Gray RH, Koenig MA, Serwadda D, Nalugoda F, Kigozi G, Sewankambo N, Lutalo T, Mangen FW, Wawer M. Alcohol Use, Intimate Partner Violence, Sexual Coercion and HIV among Women Aged 15-24 in Rakai, Uganda. AIDS Behav. 2007 Dec 7; [Epub ahead of print]

Lutalo T, Gray RH, Wawer M, Sewankambo N, Serwadda D, Laeyendecker O, Kiwanuka N, Nalugoda F, Kigozi G, Ndyanabo A, Bwanika JB, Reynolds SJ, Quinn T, Opendi P. Survival of HIV-infected treatment-naive individuals with documented dates of seroconversion in Rakai, Uganda. AIDS. 2007 Nov, 21 Suppl 6:S15-9.

Thiessen C, Ssekubugu R, Wagman J, Kiddugavu M, Wawer MJ, Emanuel E, Gray R, Serwadda D, Grady C. Personal and community benefits and harms of research: views from Rakai, Uganda. AIDS. 2007 Nov 30;21(18):2493-2501.

Gray RH, Wawer MJ. Randomised trials of HIV prevention. Lancet. 2007 Jul 21;370(9583):200-1.

Gray RH, Makumbi F, Serwadda D, Lutalo T, Nalugoda F, Opendi P, Kigozi G, Reynolds SJ, Sewankambo NK, Wawer MJ. Limitations of rapid HIV-1 tests during screening for trials in Uganda: diagnostic test accuracy study. BMJ. 2007 Jun 28;335(7612):188.

Kagulire SC, Stamper PD, Opendi P, Nakavuma JL, Mills LA, Makumbi F, Gray RH, Serwadda D, Reynolds SJ. Performance of two commercial immunochromatographic assays for rapid detection of antibodies specific to human immunodeficiency virus types 1 and 2 in serum and urine samples in a rural community-based research setting (rakai, Uganda). Clin Vaccine Immunol. 2007 Jun; 14(6):738-40.

Kagaayi J, Makumbi F, Nakigozi G, Wawer MJ, Gray RH, Serwadda D, Reynolds SJ. WHO HIV clinical staging or CD4 cell counts for antiretroviral therapy eligibility assessment. An evaluation in rural Rakai district, Uganda. AIDS. 2007 May 31; 21(9):1208-1210.

Matovu JK, Ssempijja V, Makumbi FE, Gray RH, Kigozi G, Nalugoda F, Serwadda D, Wawer MJ. Roundtable: Sexually Transmitted Infection Management, Safer Sex Promotion and Voluntary HIV Counselling and Testing in the Male Circumcision Trial, Rakai, Uganda. Reprod Health Matters. 2007 May; 15(29):68-74.

Gray RH, Li X, Kigozi G, Serwadda D, Nalugoda F, Watya S, Reynolds SJ, Wawer M. The impact of male circumcision on HIV incidence and cost per infection prevented: a stochastic simulation model from Rakai, Uganda. AIDS. 2007 Apr 23;21(7):845-850.

Ronald H Gray MD, Godfrey Kigozi MBChB, David Serwadda MBChB, Frederick Makumbi PhD, Stephen Watya MBChB, Fred Nalugoda MHS, Noah Kiwanuka MBChB, Lawrence H Moulton PhD, Mohammad A Chaudhary PhD, Michael Z Chen MSc, Nelson K Sewankambo MBChB, Fred Wabwire-Mangen PhD, Melanie C Bacon MPH, Carolyn FM Williams PhD, Pius Opendi MBChB, Steven J Reynolds MD, Oliver Laeyendecker MSc, Thomas C Quinn MD and Maria J Wawer MD. Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised trial. The Lancet, Volume 369, Issue 9562, 24 February 2007-2 March 2007, Page 615.

Gray RH, Serwadda D, Wawer MJ. Empirical observations underestimate the proportion of HIV infections attributable to sexually transmitted diseases in Mwanza and Rakai STD treatment trials: simulation results. Sex Transm Dis. 2007 Jan; 34(1): 61; author reply 62.

Ronald H Gray MD, Godfrey Kigozi MBChB, David Serwadda MBChB, Frederick Makumbi PhD, Stephen Watya MBChB, Fred Nalugoda MHS, Noah Kiwanuka MBChB, Lawrence H Moulton PhD, Mohammad A Chaudhary PhD, Michael Z Chen MSc, Nelson K Sewankambo MBChB, Fred Wabwire-Mangen PhD, Melanie C Bacon MPH, Carolyn FM Williams PhD, Pius Opendi MBChB, Steven J Reynolds MD, Oliver Laeyendecker MSc, Thomas C Quinn MD and Maria J Wawer MD. Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised trial. The Lancet, Volume 369, Issue 9562, 24 February 2007-2 March 2007, Page 615.

Gray RH, Serwadda D, Wawer MJ. Empirical observations underestimate the proportion of HIV infections attributable to sexually transmitted diseases in Mwanza and Rakai STD treatment trials: simulation results. Sex Transm Dis. 2007 Jan; 34(1): 61; author reply 62.

Matovu JK, Gray RH, Kiwanuka N, Kigozi G, Wabwire-Mangen F, Nalugoda F, Serwadda D, Sewankambo NK, Wawer MJ. Repeat voluntary HIV counseling and testing (VCT), sexual risk behavior and HIV incidence in Rakai, Uganda. AIDS Behav. 2007 Jan; 11(1): 71-8. Epub 2006 Oct 3.

Sekirime WK, Gray R. HIV Infection among Uganda Women with Cervical Cancer: a Retrospective Study. Gynecol Obstet Invest 2007; 63:222-228.

Voices from Rakai

David Serwadda

quote marker

[In Africa] we are truly at a crossroads. If we can invest in prevention, then we have a chance that we may actually reduce both incidence of the disease and make a dent in the epidemic. I really don't think we have invested in antiretroviral education in Africa the way we should have, and there isn't a good companion program at the moment in monitoring resistance. That is the capacity we're starting in Rakai...>

quote marker

David Serwadda
Founding Principal Investigator, Rakai Health Sciences Program

Center for Global Health

 

© 2016, Johns Hopkins University. All rights reserved.
Web policies, 615 N. Wolfe Street, Baltimore, MD 21205

Rakai Health Sciences Program

Johns Hopkins Bloomberg School of Public Health

Uganda Virus Research Institute

National Institute of Health