In September 2011, the Sixty-sixth session of the United Nations General Assembly acknowledged Bloomberg Philanthropies’ donation of US$ 125 million to improve global road safety. This contribution has supported the implementation of a five-year project in 10 low- and middle-income countries (LMICs) to prevent road traffic injuries, which coincides with the Decade of Action for Road Safety 2011-2020. The multi-million dollar contribution is considered the largest donation to global road safety by far.The recipients of the donation represent a global consortium on road safety. Since 2009, The Johns Hopkins University International Injuries Research Unit (JH-IIRU) has partnered with five other international institutions: the World Health Organization, the World Bank Global Road Safety Facility, the Global Road Safety Commitment, EMBARQ - the World Resources Institute Center for Sustainable Transport, and the Association for Safe International Road Travel. To date JH-IIRU has closely monitored road safety interventions in each RS-10 country and collected several rounds of primary data as regards targeted risk factors: motorcycle helmet use, seatbelt and child restraint use, speeding and drunk driving.