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Center for Clinical Trials and Evidence Synthesis Journal Club

The CCTES journal club aims to stimulate student interest, discussion and research into issues related to clinical trials and systematic reviews. Topics include trial design and data analysis; meta-analysis; medical, ethical or legal issues; data entry, management and history of clinical trials.

Schedule for 2016-2017

Schedule: Third Thursday of the month, 12:00 - 1:30PM
Location: See Below
Faculty advisors: Dr. Roberta Scherer and Dr. Ian Saldanha
Student coordinators: Jimmy Le and Ling Yang

 

Access to reading materials:
1. Go to Epi Journal Club Welch e-Reserves.
2. Click on the folder named “Clinical Trials Journal Club”.
3. Download folder contents.

 

Date
Location
Topic, Trial, Systematic ReviewStudent/Postdoc Discussant(s)Faculty Discussant(s)
September 15, 2016
E6519
The Women's Health Initiative Trials (readings)Nicole Fusco
 
Ian Saldanha
 
October 13, 2016
W2017
The Rapid Anticonvulsant Medication Prior to Arrival Trial (RAMPART) (readings)Ling Yang
 
Evan Mayo-Wilson
 
November 17, 2016
E9519
The Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Trial (readings)Amie Park
Nicole Salazar-Austin

 
Janet Holbrook
 
December 15, 2016
E6519
TBA
 
TBA
 
TBA
 
February 16, 2017
W3011
TBA
 
TBA
 
TBA
 
March 9, 2017
E9519
TBA
 
TBA
 
TBA
 
April 20, 2017
W2029
TBA
 
TBA
 
TBA
 
May 11, 2017
E6519
TBA
 
TBA
 
TBA
 

Readings:

Journal Club DateReferences
September 15, 2016
E6519





 

Required reading:
1.  Rossouw JE, Anderson GL, Prentice RL, et al.  Risks and benefits of Estrogen plus Progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial.  JAMA. 2003;288(3):321-33. 
http://www.ncbi.nlm.nih.gov/pubmed/12117397

Optional reading:
1.  Wittes J, Barrett-Connor E, Braunwald E, et al.  Monitoring the randomized trials of the Women's Health Initiative: The experience of the Data and Safety Monitoring Board.  Clin Trials.  2007;4(3):218-34.
http://www.ncbi.nlm.nih.gov/pubmed/17715247

October 13, 2016
E6519















 

Required reading:
1.  Silbergleit R, Durkalski V, Lowenstein D, et al.  Intramuscular versus Intravenous Therapy for Prehospital Status Epilepticus.  N Engl J Med.  2012;366(7):591-600.
http:www.ncbi.nlm.nih.gov/pubmed/22335736

Optional reading:
1.  Silbergleit R, Biros MH, Harney D, et al.  Implentation of the Exception from Informed Consent Regulations in a Large Multicenter Emergency Clinical Trials Network:  The RAMPART Experience.  Acad Emerg Med.  2012;19(4):448-54.
http://www.ncbi.nlm.nih.gov/pubmed/22506949

2.  Meurer WJ, Silbergleit R, Nicholas KS, et al.  Accounting for Repeat Enrollments During an Emergency Clinical Trial:  The Rapid Anticonvulsant Medications Prior to Arrival Trial (RAMPART).  Acad Emerg Med.  2015;22(3):373:77.
http://www.ncbi.nlm.nih.gov/pubmed/25715865

November 17, 2016
E9519






 

Required reading:
1. Amarenco P, Bogousslavsky J, Callahan A 3rd, et al.  High-dose Atorvastatin after Stroke or Transient Ischemic Attack.  N Eng J Med.  2006;355(6):549-59.
http://www.ncbi.nlm.noh.gov/pubmed/16899775


Optional reading:
1.  Pocock SJ and Stone GW:  The Primary Outcome Fails -- What Next?  N Engl J Med.  2016; 375(9):861-70.
http://www.ncbi.nlm.nih.gov/pubmed/2759636

 

December 15, 2016
E6519







 

Required readings:
 

Optional reading:
 

February 16, 2017
W3011

 

Required reading:


Optional reading:
 


 
March 9, 2017
E9519

 

Required reading:
 

Optional reading:
 


 

April 20, 2017
W2029

 

Required reading:
 

Optional reading:

 

May 11, 2017
E6519

 

Required reading:
 

Optional reading:
 

Information from past years:
 

Academic YearLink
2015-20162015-2016 Journal Club schedule (PDF)
2014-20152014-2015 Journal Club schedule (PDF)
2013-2014
 
2013-2014 Journal Club schedule (PDF)  
2013-2014 Journal Club schedule (HTML)
2012-20132012-2013 Journal Club schedule (PDF)
2011-20122011-2012 Journal Club schedule (PDF)
2010-20112010-2011 Journal Club schedule (PDF)
2009-20102009-2010 Journal Club schedule (PDF)
2008-20092008-2009 Journal Club schedule (PDF)
 

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