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Center for Immunization Research

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Flaviviruses Vaccine Trials at the CIR

Dengue Virus

The CIR’s experience with live attenuated recombinant chimeric vaccine candidates against dengue virus is extensive and includes the following vaccines:

  • rDEN2/4?30 (ME)
  • rDEN1?30 (ME)
  • rDEN4?30-200, 201
  • rDEN4?30-4995
  • rDEN3/4?30 (ME)

Future trials at the CIR will evaluate the rDEN4?30-7163 vaccine candidate as well as new heterologous and tetravalent candidates.

Here is a link to a list of selected publications by CIR faculty about Dengue virus.

West Nile Virus

The CIR has conducted a trial using the live attenuated recombinant chimeric vaccine candidate WN/DEN4?30, delivered in a single dose, with plans to evaluate the efficacy of a booster dose.

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Dengue Virus

West Nile Virus

Flaviviruses Vaccine Trials