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Clinical Decision Making
Clinical Decision Making
Prescription drugs are prescribed during clinical encounters. Thorough and effective patient-provider communication about the benefits, risks, costs and alternatives to prescription medicines is a vital part of clinical care. The Center supports research and advocacy to identify and overcome barriers to patient-provider communication to improve safe medication use and to maximize adherence.
Comparative Effectiveness
Comparative Effectiveness
For stakeholders to make informed decisions about prescription drug use, they need timely evidence about the comparative effectiveness of therapies and their alternatives, including their risks and benefits. Incomplete evidence contributes to overuse of some therapies, underuse of others and risky prescribing. The Center supports innovative research into these topics.
Global Medicines
Global Medicines
Ensuring adequate access and affordability of prescription medicines poses major and unique challenges for countries around the world. These challenges are particularly salient in emerging economies that account for an increasing proportion of the world's population and pharmaceutical expenditures. Center investigators focus on how public policy can be optimized to maximize global drug availability and access.
Medication Safety
Medication Safety
Some adverse effects of medicines only come to light after medications have been on the market and widely used. Center investigators are working to develop new methods for identifying risk, to predict the likelihood of high-risk medicines or drug combinations and to protect the public from excessive exposure to these products.
Policy Analyses
Policy Analyses
Complex and dynamic policies govern prescription drug regulation. Policymakers face the challenge of maximizing innovation while protecting public health, and developing payment policies that promote evidence-based usage. Center investigators evaluate regulatory policies to provide policymakers with information to continually optimize pharmaceutical regulation.
Prescription Abuse
Prescription Abuse
Prescription drugs provide therapeutic value to millions of Americans. At the same time, rates of prescription drug abuse and overdose deaths are skyrocketing. The annual number of fatal drug overdoses in the United States now surpasses those of motor vehicle deaths. The Center supports innovative research and public advocacy to help stem this epidemic.

Previous Seminars

How to Make Healthcare Data Exchange Work
Kenneth Park, MD

Turning Public Health Data into Action: Preventing Medication Overdoses in Young Children, Developments over a Decade
Daniel Budnitz, MD, MPH, CAPT USPHS
(PDF)

A Case for Why Health Systems Should Partner with Pharmacies
William Shrank, MD, MSHS

21st Century Cures Act: A Requiem for a Dying Piece of Legislation
Aaron Kesselheim, MD, JD, MPH

Propensity Score Methods in Pharmacoepidemiology with Emphasis on Variable Selection and Balance Measures
M. Sanni Ali, PhD
(PDF)

Expanding Role of Epidemiology in the Pharmaceutical Industry with Post-Authorization Safety Studies
Nancy Santanello, MD, MS, FISPE
(PDF)

Confounding in Pharmacoepidemiology: I Know It When I See It
John W. Jackson, ScD

Pharmacoepidemiology and the Regulation of Medicines
Gerald J. Dal Pan, MD, MHS
(PDF)

Open Access to Trials Data: Will It Give Us All That We Need?
Evan Mayo-Wilson, DPhil, MPA

Putting Pharmacoepidemiology into Practice
Panel of Core Faculty

Comparative Effectiveness of Intravenous Iron Formulations in Hemodialysis Patients
M. Alan Brookhart, PhD

Digiceuticals "We don't make the drug, we make the drug work better": Fact or Fiction or Too Soon to Tell?
Caroline Popper, MD, MPH
(PDF)

FDA as a Public Health Agency
Joshua Sharfstein, MD

Managing a Complex Medical/Legal/Scientific Organization for the Public Benefit
Janet Woodcock, MD
(PDF)

Medication Safety: Lessons Learned from a National Medication Error Reporting Program
Michael Cohen, RPh, MS

The Future for Drug Development in an Increasingly Evidence-Based Environment
Jonothan C. Tierce, C.Phil
(PDF)

Driving Innovation in Big Pharma
Robert Carr, MD, MPH

Big Data meets Real World Data and the Future of Comparative Effectiveness Research
Marc Berger, MD

The Two Way Mirror: Reflections on Life in Academic and Industrial Research
Craig Smith, MD

The Trillion Dollar Market for Medicines: Characteristics, Dynamic and Outlook
Murray Aitken, MBA
(PDF)

Approaches to Studying Medication Safety in Children: The Case of Leukotriene-Modifying Agents and Suicide
Glen Schumock, PharmD, MBA, PhD

PAY ATTENTION: Covering Trends in ADHD Medication Among American Youth
Alan Schwarz

Comparative Harms of Anti-Epilepsy Medications
Sean Sullivan, PhD, BScPharm
(PDF)

Regulatory Statistics in FDA's Center for Drug Evaluation and Research
Lisa LaVanve, PhD
(PDF)

Studying the Clinical Importance of Drug-Drug Interactions
Sean Hennessey, PharmD, PhD

Prescription Opioid Poisonings and State Prescription Drug Monitoring Programs
Michael Kim, MPH
(PDF)

Barriers to Delivery of Pharmacologic Venous Thromboembolism Prophylaxis
Stacy Elder, PharmD, BCPS

Diuretic Use, Urate Handling Genes, and Gout
Mara McAdams DeMarco, PhD

Insight into the Drug Use Evaluation (DUE) Process: Assessment of Dabigatran at Johns Hopkins
Emily Pherson, PharmD and Raymond Lamore, PharmD
(PDF)

Safety of the Novel Anticoagulants VS Warfarin: A Comparative Evaluation
Sonal Singh, MD, MPH, PhD Candidate
(PDF)

Patterns of Concomitant Antipsychotic Use Among Youth in Foster Care: Issues of Quality of Care and Safety
Susan dosReis, PhD
(PDF)

Partnership in Applied Comparative Effectiveness Science Initiative: Hopkins and FDA
Jodi Segal, PhD, MPH
(PDF)

Ambulatory Treatment of Pain and Opioids: New Challenges for Drug Safety
G. Caleb Alexander, MD, MS
(PDF)

Impact of 2012 Fungal Meningitis Outbreak Upon Patients who were Exposed but did not Develop Infection
Shmuel Shoham, MD
(PDF)

The Healthy User Effect: Ubiquitous and Uncontrollable
Sumit Majumdar, MD, MPH
(PDF)

Responding to the Joint Commission Alert on Safe Use of Opioids in Hospitals
Suzanne Nesbit, PharmD
(PDF)

Role of the Pharmacy & Therapeutics Committee in the Academic Medical Center
Brent Petty, MD
(PDF)

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