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Clinical Decision Making
Clinical Decision Making
Prescription drugs are prescribed during clinical encounters. Thorough and effective patient-provider communication about the benefits, risks, costs and alternatives to prescription medicines is a vital part of clinical care. The Center supports research and advocacy to identify and overcome barriers to patient-provider communication to improve safe medication use and to maximize adherence.
Comparative Effectiveness
Comparative Effectiveness
For stakeholders to make informed decisions about prescription drug use, they need timely evidence about the comparative effectiveness of therapies and their alternatives, including their risks and benefits. Incomplete evidence contributes to overuse of some therapies, underuse of others and risky prescribing. The Center supports innovative research into these topics.
Global Medicines
Global Medicines
Ensuring adequate access and affordability of prescription medicines poses major and unique challenges for countries around the world. These challenges are particularly salient in emerging economies that account for an increasing proportion of the world's population and pharmaceutical expenditures. Center investigators focus on how public policy can be optimized to maximize global drug availability and access.
Medication Safety
Medication Safety
Some adverse effects of medicines only come to light after medications have been on the market and widely used. Center investigators are working to develop new methods for identifying risk, to predict the likelihood of high-risk medicines or drug combinations and to protect the public from excessive exposure to these products.
Policy Analyses
Policy Analyses
Complex and dynamic policies govern prescription drug regulation. Policymakers face the challenge of maximizing innovation while protecting public health, and developing payment policies that promote evidence-based usage. Center investigators evaluate regulatory policies to provide policymakers with information to continually optimize pharmaceutical regulation.
Prescription Abuse
Prescription Abuse
Prescription drugs provide therapeutic value to millions of Americans. At the same time, rates of prescription drug abuse and overdose deaths are skyrocketing. The annual number of fatal drug overdoses in the United States now surpasses those of motor vehicle deaths. The Center supports innovative research and public advocacy to help stem this epidemic.


Affiliated with both the Johns Hopkins Bloomberg School of Public Health and Johns Hopkins Medicine, the Center faculty reflect the tremendous breadth and depth of human capital within the Johns Hopkins community, and represent fields of expertise ranging from drug hypersensitivity to regulatory science to psychiatric pharmacoepidemiology. If you are interested in becoming a core faculty member, please contact us.

Core Faculty

adkinsonFranklin Adkinson, MD
Professor of Medicine in Allergy and Clinical Immunology
Expertise: Drug hypersensitivity, immunotherapy, natural history and management of allergic asthma, diagnosis and evaluation of drug allergies

alexanderG. Caleb Alexander, MD, MS
Associate Professor of Epidemiology and Medicine
Expertise: Drug utilization, patient-provider decision making, effects of regulatory and payment policies

blankAdriana Andrade, MD
Assistant Professor of Medicine, Infectious Disease
Expertise: Drug interactions, compliance, pharmacology


burkeThomas Burke, PhD, MPH
Professor of Health Policy and Management; Associate Dean for Public Health Practice and Training
Expertise: Application of epidemiology and health risk assessment to public policy

changHsien-Yen Chang, PhD, MHS, MS
Assistant Scientist in the Department of Health Policy and Management
Expertise: Statistical methods in analyzing medical utilization, risk adjustment and its applications, outcome evaluation and cost-effectiveness analysis

colonnaTom Colonna, JD, PhD
Associate Director of Regulatory Science, Advanced Academic Program
Krieger School of Arts and Sciences
Expertise: Regulatory Science

G Dal PanGerald Dal Pan, MD, MHS
Adjunct Assistant Professor of Neurology


dickersinKay Dickersin, PhD
Professor of Epidemiology; Director of the Center for Clinical Trials; Director of the US Cochrane Center
Expertise: Randomized clinical trials, trial registers, systematic reviews and meta-analysis; evidence-based health care

blankMaria Eng, DrPH, MPH
Associate, Departments of International Health, and Health, Behavior and Society
Expertise: Pharmaceuticals management in developing countries and underserved populations, medication access and adherence, peer education, community participation, program development and evaluation

feroliBob Feroli, PharmD, FASHP, FSMSO
Associate Professor and Medication Safety Officer
Department of Pharmacy
Expertise: Medication safety

Steve Gange, PhDgange
Professor of Epidemiology
Expertise: Epidemiologic and statistical methods for cohort studies, evaluation of therapies and biomarkers in observational studies, epidemiology and pathogenesis of HIV/AIDS

greeneJeremy Greene, MD, PhD
Associate Professor, Elizabeth Treide and A. McGehee Harvey Chair in the History of Medicine
Expertise: History of therapeutics, especially the pharmaceutical industry; history of medicine and global health

hendrixCraig Hendrix, MD
Professor of Medicine, Pharmacology and Molecular Sciences and Epidemiology; Director, Drug Development Unit
Expertise: Chemoprevention of HIV infection, topical HIV microbicides, clinical pharmacology of antiviral drugs, drug interactions

holbrookJanet Holbrook, PhD, MPH
Associate Professor of Epidemiology
Expertise: Design, conduct and analysis of multi-center clinical trials

hutflessSusan Hutfless, PhD
Instructor of Medicine
Expertise: Pharmacotherapy in inflammatory bowel disease


stefanStefan P. Kruszewski, MD
Assistant Professor of Mental Health
Expertise: Neuropsychiatry and Addiction Medicine


liTianjing Li, MD, MHS, PhD
Assistant Professor of Epidemiology
Expertise: systematic reviews, meta-analysis, network meta-analysis, randomized controlled trials, reporting biases, missing data, comparative effectiveness research, patient-centered outcomes research.

LylesAlan Lyles, BSPharm, MPH, ScD
Adjunct Associate Professor of Health Policy and Management
Expertise: Public-, private- and third-sector arrangements, pharmaceutical economics and health policy, prevention and treatment of obesity, substance abuse and other lifestyle consequences

marrKieren Marr, MD
Professor of Oncology, Sidney Kimmel Cancer Center Director
Transplant and Oncology Infectious Disease Program
Expertise: Antimicrobials,diagnostic devices, epidemiologic studies in medically immunosuppressed hosts

blankMara McAdams-DeMarco, PhD, MS
Instructor of Surgery; Core Faculty, Welch Center
Expertise: Cardiovascular and renal pharmacoepidemiology


mojtabaiRamin Mojtabai, MD, PhD
Associate Professor of Mental Health
Expertise: Pharmacoepidemiology of psychiatric drugs, mental health services research including trends and correlates of use of services, barriers to accessing services, process and outcome of treatments

mooreRichard Moore, MHS, MD
Professor of Medicine; Director, Moore Clinic for HIV Care
Expertise: Pharmacoepidemiology, outcomes research in HIV treatment, epidemiology of substance abuse and alcoholism

Suzanne Nesbit, PharmD, BCPSpetty
Clinical Pharmacy Specialist, Pain Management; Clinical Coordinator, Cancer Pain Service; Research Associate, Department of Oncology at The Sidney Kimmel Comprehensive Cancer Center
Expertise: Pain Management

Brent Petty, MDpetty
Associate Professor, Departments of Medicine and Clinical Pharmacology
Expertise: Clinical pharmocology


Brian Pinto, PharmD, MBApetty
Assistant Director of Medication Use Policy and Clinical Informatics, Department of Pharmacy at The Johns Hopkins Hospital
Expertise: Clinical pharmocology

Debra Roter, DrPH, MPHpetty
Professor, Department of Health, Behavior and Society
Expertise:Patient-provider communication; she is the author of the Roter Interaction Analysis System (RIAS) developed as method of process analysis applied to audio or video recordings of medical encounters.


Daniel Scharfstein, PhD
Professor of Biostatistics
Expertise: Frequentist and Bayesian approaches to evaluate robustness of assumptions in studies with missing/censored data, high mortality rates, non-compliance, uncontrolled treatment assignment

segalJodi Segal, MD, MPH
Associate Professor of Medicine, Epidemiology and Health Policy and Management
Expertise: Pharmacoepidemiology, comparative effectiveness research, evidence-based review, advanced methods for using observational data

Joshua SharfsteinJoshua Sharfstein, MD
Associate Dean
Public Health Practice and Training


Ken ShermockKen Shermock, PharmD, PhD
Director, Center for Pharmaceutical Outcomes and Policy at Johns Hopkins Hospital
Expertise: Medication safety and quality in the hospitalized setting

singhSonal Singh, MD
Assistant Professor of Medicine and International Health
Expertise: Pharmaceutical outcomes research, drug safety and pharmacoepidemiology


stuartEric Strain, MD
Professor,  Psychiatry and Behavioral Sciences; Director, Johns Hopkins Center for Substance Abuse Treatment and Research
Expertise: Clinical research in substance abuse, including medications development, abuse liability testing, psychiatric comorbidity, and behavioral interventions

stuartElizabeth Stuart, PhD
Associate Professor in Mental Health and Biostatistics
Expertise: Statistical methodology for mental health research, particularly relating to causal inference and missing data

stuartRavi Varadhan, PhD (Biostatistics), PhD (Environmental Engineering)
Associate Professor, Division of Geriatric Medicine & Gerontology
Expertise: Mathematical approaches for characterizing the homeostatic impairments underlying the geriatric syndrome of frailty; flexible regression modeling approaches for risk-factor etiology and prediction in observational studies of geriatric syndromes.  

taoXuguang (Grant) Tao, MD, PhD
Associate Professor and Research Director
Expertise: Environmental and occupational epidemiology research, GIS applications in environmental epidemiologic research, workers' compensation and Injuries, and nosocomial infections

zandiPeter Zandi, PhD, MPH, MHS
Associate Professor, Mental Health
Expertise: Genetic epidemiology of psychiatric disorders, pharmacoepidemiology of psychotropic drugs, pharmacogenetics of psychotropic drugs



Matt Daubresse, MHS
Research Data Analyst

Eleanor Lucas
Research Program Coordinator

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