Role of polycyclic aromatic hydrocarbons (PAH) in Esophageal Cancer in High Risk Areas
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This project is an international collaboration with investigators at the International Agency for Research on Cancer (IARC) and the National Cancer Institute (NCI) to explore the hypothesis that dietary polycyclic aromatic hydrocarbons (PAH) may play a role in causing elevated rates of esophageal cancer (squamous cell carcinoma) in certain regions. Pilot studies using urinary 1-hydroxypyrene as a biomarker of PAH exposure have been conducted in Linxian, China; Golestan, Iran; and Rio Grande do Sul, southern Brazil.