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Brad Sack, MD

  • Professor

Departmental Affiliations

Center & Institute Affiliations

Contact Information

615 N. Wolfe Street
Room W5035
Baltimore, Maryland 21205



MD, University of Oregon Medical School, 1960
ScD, Johns Hopkins Bloomberg School of Public Health, 1968
MS, University of Oregon Medical School, 1960


Cholera and other diarrheal diseases are the focus of my research. I began work on cholera in Calcutta in 1952 and have continued that work to the present. Studies included microbiology, treatment, epidemiology and ecology. In 1968 our lab discovered enterotoxigenic E. coli, which is known as the most frequent bacterial cause of diarrhea in small children living in the developing world. Also during 1968, I helped in the discovery, development, and subsequent teaching of oral rehydration therapy for the treatment of secretory diseases. From the 1970s to the present, I have conducted studies of the epidemiology and ecology of cholera in rural Bangladesh.

Honors and Awards

1956 - Lewis and Clark College, Portland, Oregon: Graduated summa cum laude.

1956-1960 - University of Oregon Medical School: Selling Scholarships for two years, graduated with highest honors, elected to Alpha Omega Alpha junior year. 

1987 - Lewis and Clark College, Portland, Oregon: Distinguished Alumni Award.

1990 - Lewis and Clark College, Portland, Oregon: Delta Omega Public Health Honorary Society, Alpha Chapter. Phi Beta Kappa, elected as alumni member.

2003 - Peruvian National Academy of Medicine: Elected in September.

2007 - Johns Hopkins Medical and Surgical Association: Samuel P. Asper Award for Achievement for Advancing International Medical Education. 

  • diarrhea cholera enterotoxigenic E. coli India Bangladesb Epidemiology Ecology
  • Recent publications from total of 283

  • Sack, DA, Sack RB, Chaignat CL. Getting serious about cholera, NEJM, 2006,355:640-651

  • Huq A, Sack RB, Nizam A, Longini IM, Nair GB, Ali A, Morris JG Jr, Khan MN, Siddique AK, Yunus M, Albert MJ, Sack DA, Colwell RR. Critical factors influencing the occurrence of Vibrio cholerae in the environment of Bangladesh. Appl Environ Microbiol. 2005 Aug;71(8):4645-54.

  • .Sack RB. Prophylactic antimicrobials for traveler's diarrhea: an early history. Clin Infect Dis. 2005 Dec 1;41 Suppl 8:S553-6.

  • .Qadri F, Ahmed T, Ahmed F, Sack RB, Sack DA, Svennerhollm, AM, PTE study group, Safety and immunogencitiy of an oral, inactivated enterotoxigenic Eschierichi coli plus cholera toxin B subunit vaccine in Bangladesh children, 18-36 months of age, Vaccine, 2003 21 :3994-2403