Skip Navigation

Faculty Directory

Bruce Lee, MD

  • Director, Global Obesity Prevention Center (GOPC) at Johns Hopkins
  • Director, Operations Research, International Vaccine Access Center (IVAC)
  • Associate Professor

Departmental Affiliations

Center & Institute Affiliations

Contact Information

615 N. Wolfe Street
Room W3503
Baltimore, Maryland 21205


Huffington Post:


MD, Harvard Medical School, 1994
MBA, Stanford School of Business, 1998


Dr. Lee has over 15 years of experience in industry and academia in public health operations research, which involves developing and utilizing mathematical and computational methods, models, and tools to help stakeholders better understand decision making, processes, and systems.  He has been the Principal Investigator for grants from a variety of sponsors including the Bill and Melinda Gates Foundation, the National Institutes of Health (NIH), the Agency for Healthcare Quality and Research (AHRQ), UNICEF, Global Good, and the Global Fund.

His previous positions include serving as Senior Manager at Quintiles Transnational where he led teams that developed economic and operational models for a variety of clients in the pharmaceutical, biotechnology, and medical device industries, working in biotechnology equity research at Montgomery Securities, and co-founding Integrigen, a biotechnology/bioinformatics company, and serving as an Associate Professor at the University of Pittsburgh, where he founded PIHCOR (Public Health Computational and Operations Research), which is now based at Johns Hopkins.

 Dr. Lee has authored over 160 scientific publications (including over 80 first author and over 35 last author) as well as three books: “Principles and Practice of Clinical Trial Medicine”, “What If… ? : Survival Guide for Physician’s, and “Medical Notes : Clinical Medicine Pocket Guide”. He is an Associate Editor for the journal Vaccine and Area Series Editor for the Wiley Series on Modeling and Simulation. He and his work have garnered attention in leading media outlets such as the New York Times, Los Angeles Times, Businessweek, U.S. News and World Report, Bloomberg News, Nature Medicine, and National Public Radio (NPR). His blog on the Huffington Post is at:

  • operations research
  • computational methods, modeling, and tools
  • systems science

Visualization of the Republic of Benin vaccine supply chain, generated via our HERMES supply chain simulation modeling software platform.

Five sample publications from different major projects over the past 4 years.  Selected from over 160 scientific publications (including over 80 first author and over 35 last author) 

  • Lee, B.Y., Bartsch, S.M., Wong, K.F., Yilmaz, S.L., Avery, T.R., Singh, A., Song, Y., Kim, D.S., Brown, S.T., Potter, M.A., Platt, R., Huang, S.S. (2012) Simulation shows hospitals that cooperate on infection control obtain better results than hospitals acting alone. Health Affairs, 31(10):2295-2303. PMID: 23048111.

  • Lee, B.Y., Bacon, K.M., Bottazzi, M.E., Hotez, P.J.  (2013) A computational simulation model: the global economic burden of Chagas' Disease.  Lancet Infectious Diseases, 13(4):342-348. PMID: 23395248.

  • Lee, B.Y., Brown, S.T., Bailey, R.R., Zimmerman, R.K., Potter, M.A., McGlone, S.M., Cooley, P., Grefenstette, J.J., Zimmer, S.M., Potter, M.A., Wheaton, W.D., Quinn, S.C., Voorhees, R, and Burke, D.S. (2011) The benefits to all of ensuring equal and timely access to influenza vaccines in poor communities.  Health Affairs. 30(6):1141-1150. PMID: 21653968.

  • Lee, B.Y., McGlone, S.M., Song, Y., Avery, T.R., Eubank, S., Chang, C., Bailey, R.R., Wagnener, D.K., Burke, D.S., Platt, R., and Huang, S.S. (2011) Social network analysis of patient sharing among hospitals in Orange County, California. American Journal of Public Health, 101(4):707-713. PMID: 21330578.

  • Lee, B.Y., Cakouros, B.E., Assi, T.M., Connor, D.L., Welling, J., Kone, S, Djibo, A., Wateska, A.R., Pierre, L., Brown, S.T. (2012)The impact of making vaccines thermostable in Niger’s vaccine supply chain. Vaccine, 30(38):5637-5643 PMID: 22789507.