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G. Caleb Alexander, MD

Co-Director, Center for Drug Safety and Effectiveness

Associate Professor

Departmental Affiliation(s):

Epidemiology

Center & Institute Affiliation(s):

Contact Information

615 N. Wolfe Street
Room W6035
Baltimore , Maryland   21205
US        

410-955-8168
410 955 0863

Center for Drug Safety and Effectiveness: www.jhsph.edu/cdse

Education

MD , Case Western Reserve University , 1998
MS , University of Chicago , 2003

Overview

Dr. Alexander is a practicing general internist and pharmacoepidemiologist who is nationally renowned for his work examining prescription drug utilization.  He is an Associate Professor in the Departments of Epidemiology and Medicine and co-Director of the Johns Hopkins Center for Drug Safety and Effectiveness.  His work focuses on population-based patterns and determinants of pharmaceutical use, clinical decision-making regarding prescription drugs, and the impact of changes in regulatory and payment policy on pharmaceutical utilization.  In addition to expertise conducting survey-based investigations, Dr. Alexander has also extensive experience with the analysis of secondary data sources including administrative claims, the Medical Expenditure Panel Survey and the National Ambulatory Medical Care Survey. Dr. Alexander is the author of more than one hundred peer-reviewed publications and is an ad hoc member of the FDA Drug Safety and Risk Management Advisory Committee.  He is currently the Principal or Co-Principal Investigator of RO1s from the AHRQ and the NHLBI that examine the effect of FDA regulatory communications and direct-to-consumer advertising on prescription and non-prescription health care utilization.

Dr. Alexander has served on numerous editorial boards including Drug SafetyMedical Care, Medical Decision Making, American Journal of Health-System Pharmacy and the Journal of General Internal Medicine.

Research Interests: prescription drugs; drug utilization; drug safety; drug effectiveness; pharmacoepidemiology; pharmaceutical policy

Honors and Awards

Honors

1993 Cum Laude, University of Pennsylvania

1997 Alpha Omega Alpha, Case Western Reserve University

2003-2005  John A. Oremus Memorial Scholar ($40,000 Research Stipend), MacLean Center for Medical Ethics, University of Chicago

2006 Top 5% of reviewers, Medical Care (also received annually through 2011)

2007 Top 10% of reviewers, Ann Intern Med (also received annually through 2009)

2011 Elected Fellow of the American College of Physicians (FACP)

 

Awards

2001 Edward W. Holmes Resident Research Award, University of Pennsylvania

2006-2009  Robert Wood Johnson Foundation Faculty Scholar

2007 Research Finalist, International Society for Pharmacoeconomics and Outcomes Research, Annual Meeting

2008 Outstanding Physician Scientist Award, Central Society for Clinical Research

2008 Career development award ($10,000 Research Stipend), Central Society for Clinical Research

2008 Department of Medicine Research Award (awarded to trainee for mentored research; also received by mentored trainees in 2009 and 2010)

2009 Pritzker School of Medicine Sigma Xi Award for Impact on Science (awarded to trainee for mentored research)

prescription drugs; drug utilization; drug safety; drug effectiveness; patient-provider communication; pharmacoepidemiology; regulatory policy; Food and Drug Administration

    Select Peer-Reviewed Publications (of over 125 total; trainees' names are underlined)

  • Yin W, Basu A, Zhang J, Rabbani A, Meltzer DO, Alexander GC.  Impact of the Medicare Part D Prescription Drug Benefit on drug utilization and out-of-pocket expenditures. Annals of Internal Medicine.  2008;148:169-177.

  • Dorsey R, Rabbani A, Gallagher SA, Conti R, Alexander GC.  The impact of black box warnings on the use of atypical antipsychotic medicines.  Archives of Internal Medicine.  2010;170:96-103.   

  • Dusetzina SBHigashi A (*co-first author), Dorsey ER, Conti R, Huskamp HA, Zhu S, Garfield CF, Alexander GC.  Impact of FDA risk communications on health care utilization and health behaviors: a systematic review.  Medical Care.  2012;50:466-78.

  • Kirley KQato DMKornfield R, Stafford RS, Alexander GC.  National trends in oral anticoagulant use in the United States, 2007-2011.  Circulation: Cardiovascular Outcomes and Quality.  2012;5:615-621.

  • Daubresse M, Chang H-Y, Yu Y, Viswanathan S, Shah ND, Stafford RS, Kruszewski SP, Alexander GC.  Ambulatory Diagnosis and Treatment of Non-Malignant Pain in the United States, 2000-2010.  Medical Care.  2013;51:870-8.