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Efe Sezgin, PhD

Department of Epidemiology

Research Associate

Departmental Affiliation(s):

Epidemiology

Education

PhD , Stony Brook University , 2005

Overview

My research program investigates the origin, extent, and dynamics of natural variation in human genome and how this variation at the DNA sequence level translates into complex phenotypic variation among human groups. Infectious disease susceptibility, cancers, autoimmune disorders, and (accelerated) aging are good examples of complex phenotypes whose genetic architecture and interactions with non-genetic factors are yet to be discovered. 

Specific research projects include human evolutionary history, population structure and mapping of disease genes; Genomic approaches to identify biological pathways influencing HIV infection, progression, and therapy response; Ocular complications, opportunistic infections and cancers among HIV-infected patients; HIV/AIDS and aging; and Mendelian diseases as models for complex disorders

Honors and Awards

2010         Office of AIDS Research-Intramural Research Grant (Topic: Genome-wide association study to identify host genetic risk factors for susceptibility to HIV infection and progression to AIDS related outcomes among African Americans)

2010             FARE Travel award

2006-2011    National Institutes of Health Postdoctoral Training Fellowship

2003             Full scholarship from University of Tennessee-Knoxville to attend courses on the mathematics of biological complexity

2002             Full scholarship from North Carolina State University to attend Summer          Institute in Statistical Genetics 

Genetics, genomics, infectious disease, AIDS, Aging