Kawsar R. Talaat,
Center & Institute Affiliation(s):
My current research focuses on clinical trials of vaccines for potential pandemic influenza strains. At the Center for Immunization Research, we conduct phase I and II clinical trials of vaccine candidates for many diverse pathogens. As part of the Pandemic Influenza Preparedness and Response Plan, we plan and execute phase I trials evaluating the safety and immunogenicity of a number of influenza vaccine candidates targeting strains with pandemic potential. Also, as I am trained in Infectious Diseases and parasitology, I retain an interest in tropical medicine and international health.
International Health, Vaccines, Avian Influenza, Pandemic Influenza, Parasitology
Talaat, K. R., Karron, R. A., Luke, C. J., Thumar, B., McMahon, B. A., Chen, G. L., Lamirande, E. W., Jin H., Coelingh, K. L., Kemble, G. and Subbarao, K. An open label Phase 1 trial of a live attenuated H6N1 influenza virus vaccine in healthy adults. Vaccine, 2011. In Press, Available online 4 March 2011.
Ramanathan, R., Talaat, K. R., Fedorko, D.P., Mahanty, S., and Nash, T.E. A species-specific approach to the use of non-antimony treatments for Cutaneous Leishmaniasis. Am J Trop Med Hyg 2011; 84(1):109-17.
Talaat, K. R., Greenberg, M. E., Lai, M. H., Hartel, G. F., Wichems, C. H., Rockman, S., Jeanfreau, R. J., Ghosh, M. R., Kabongo, M. L., Gittleson, C., and Karron, R. A., A single dose of unadjuvanted novel 2009 H1N1 vaccine is immunogenic and well tolerated in young and elderly adults. J Infectious Diseases 2010; 202(9): 1327-37.
Talaat, K. R., Rothman, J. A., Cohen, J. I., Santi, M., Rorke-Adams, L. B., Choi, J. K., Guzman, M., Zimmerman, R., Nallasamy, S., Brucker, A., Quezado, M., Pittaluga, S., Patronas, N. J., Klion, A. D. and Nichols, K. E. Lymphocytic vasculitis involving the central nervous system occurs in patients with X-linked lymphoproliferative disease in the absence of Epstein Barr virus infection. Pediatric Blood and Cancer 2009; 53(6):1120-3.
Talaat, K. R., Karron, R. A., Callahan, K. A., Luke, C., DiLorenzo, S., Chen, G., Lamirande, E., Jin, H., Coelingh, K., Kemble, G., and Subbarao, K. A live attenuated H7N3 influenza virus vaccine is well-tolerated and immunogenic in healthy adults. Vaccine 2009; 27: 3744-3753.