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Sarah Wheelan, MD

Assistant Professor

Departmental Affiliation(s):

Biostatistics (Joint)

Contact Information

550 N. Broadway Suite 1103
Baltimore , Maryland   21205
US        

410-502-7754

Lab site: http://sjwheelan.som.jhmi.edu/
Center for Computational Genomics: http://genomics.jhu.edu/
Next Generation Sequencing Center, SKCCC: http://ngsc.onc.jhmi.edu/

Education

MD
PhD

Overview

Areas of interest:

* Sequence alignment * Transposons and repetitive elements * Eukaryotic gene regulation * Motifs * Microarray analysis * Microarray design (including a unique double-tiling approach)

Teaching:

* Analysis of Biological Sequences * Guest lecturer for Jonathan Pevsner's introductory Bioinformatics course

Software projects:

* Spidey— a spliced alignment algorithm * GeneDesign— synthetic gene construction

  • Wheelan SJ, Martinez-Murillo F, Boeke JD. The incredible shrinking world of DNA microarrays. Molecular BioSystems, in press.

  • Boeke JD, An W, Dai L, Davis ES, Han JS, O'Donnell KA, Scheifele LZ, Wheelan SJ Retrotransposons — Natural and Synthetic. In Retrotransposition, Diversity and the Brain. Fred Gage (Editor), Yves Christen (Editor) First Edition, 2007.

  • An W, Han JS, Wheelan SJ, Davis ES, Coombes CE, Ye P, Triplett C, Boeke JD. Active retrotransposition by a synthetic L1 element in mice. Proc Natl Acad Sci U S A. 103(49):18662-7, 2006.

  • Wheelan SJ, Scheifele LZ, Martinez-Murillo F, Irizarry RA, Boeke JD. Transposon insertion site profiling chip (TIP-chip). Proc Natl Acad Sci U S A. 103(47):17632-7, 2006.

  • Wheelan SJ, Martinez-Murillo F, Boeke JD. Stacking the deck: double-titled DNA microarrays. Nature Methods, 3(11):903-7, 2006.