Sungano Mharakurwa, DPhil
Senior Research Associate
Center & Institute Affiliation(s):
DPhil , University of Oxford , 2001
MSc , University of London
Investigating public health strategies for delaying or minimizing the evolution of Plasmodium falciparum resistance to antimalarial drugs. Currently examining the field dynamics and determinants of drug-resistant P. falciparum alleles in human and vector phases in order to identify potential targets for containment approaches. Previous work included the relationship of Plasmodium falciparum transmission control on levels of multigenic drug resistance. Parallel studies explore the development of non-invasive methods for the detection of P. falciparum malaria using human saliva and urine samples.
Honors and Awards
Nature Publishing Group travel Award, February 2009
Gordon Research Conference guest speaker, February 2009
MIM IVth Pan African Malaria Conference travel Award, November 2005
Young Scientist Travel Award, XIVth International Congress on Tropical Medicine and Malaria, 1996
Malaria, Plasmodium falciparum, transmission, drug resistance, detection, saliva, evolution, control
Mharakurwa S., Kumwenda T, Mkulama MA, Musapa M, Chishimba S, Shiff CJ, Sullivan D.J., Thuma P.E., Liu K., Agre P. (2011) Malaria antifolate resistance with contrasting Plasmodium falciparum dihydrofolate reductase (DHFR) polymorphisms in humans and Anopheles mosquitoes. Proceedings of the National Academy of Sciences of the U S A. 2011 Nov 15;108(46):18796-18801. Epub 2011 Nov 7. PubMed PMID: 22065788.
Sutcliffe C.G., Kobayashi T., Hamapumbu H., Shields T., Kamanga A., Mharakurwa S., Thuma P., Glass G. and Moss W.(2011) Changing individual-level risk factors for malaria with declining transmission in southern Zambia: a cross-sectionalstudy. Malaria Journal 10(1): 324
Pooe O.J., Shonhai A and Mharakurwa S. (2011) A PCR screen for malaria carrier infections using human saliva samples African Journal of Microbiology Research 5 (28) 5120-5126.
Sutcliffe C.G., Kobayashi T., Hamapumbu H., Shields T., Kamanga A., Mharakurwa S., Thuma P.E., Glass G., Moss W.J. (2011) Changing individual-level risk factors for malaria with declining transmission in southern Zambia: a cross-sectional study. Malar J. Oct 31;10(1):324.
Davis R.G., Kamanga A., Castillo-Salgado C., Chime N., Mharakurwa S., Shiff C. (2011) Early detection of malaria foci for targeted interventions in endemic southern Zambia. Malar J. Sep 12;10:260.