Maria Knoll, PhD
- Associate Scientist
- Division: Health Systems
Center & Institute Affiliations
855 N. Wolfe St
PhD, Johns Hopkins University, 2000
My research interests include the epidemiology of vaccine-preventable infectious diseases and the methodologic issues pertaining to the design, conduct and analysis of epidemiologic studies and clinical trials. Currently I serve as the Associate Director of Science for IVAC (International Vaccine Access Center). Current projects include the PERCH Study to determine the causes of pneumonia in settings representative of developing countries to guide the development of new pneumonia vaccines and treatment algorithms for 2015 onwards, estimating the burden and serotype distribution of pneumococcal and meningococcal disease among children and adults, measuring the impact on disease burden of pneumococcal conjugate vaccine use in Kenya and The Gambia, and evaluating the value of antigen-based diagnostic tests in blood to improve sensitivity of pneumococcal detection in pneumonia patients.
Honors and Awards
National Institutes of Health Merit Award (1999,1991) Food and Drug Administration Commissioner’s Special Citation Group Award (1997) U.S. DHHS Secretary’s Group Award for Distinguished Service (1996) U.S. DHHS Special Achievement Award (1995,1991)
- vaccines, international health, S. Pneumoniae, H. influenzae, pneumonia, vaccine preventable diseases, epidemiology, clinical trials
Deloria-Knoll M, E Henkle, E Lee, N McCall, J Moisi, J Watt, K O’Brien and the Hib and Pneumococcal Global Burden of Disease Working Group. Global literature review of Haemophilus influenzae type b and Streptococcus pneumoniae invasive disease among children less than five years of age, 1980-2005. WHO report. 2009; WHO/IVB/09.02. http://whqlibdoc.who.int/hq/2009/WHO_IVB_09.02_eng.pdf
Deloria Knoll M, Moïsi JC, Muhib FB, Wonodi CB, Lee EH, Grant L, Gilani Z, O’Brien KL, Cherian T, Levine OS and the PneumoADIP-Sponsored Surveillance Investigators. Standardizing Surveillance for Pneumococcal Disease. Clin Infect Dis. 2009;48 Suppl 2:S37-48.
Moïsi JC, SK Saha, AG Falade, BM Njanpop-Lafourcade, J Oundo, AKM Zaidi, S Afroj, RA Bakare, JK Buss, R Lasi, AA Odekanmi, L Sangaré, JAG Scott, MD Knoll, OS Levine and BD Gessner. Enhanced diagnosis of pneumococcal meningitis with use of the Binax NOW immunochromatographic test of Streptococcus pneumoniae antigen: a multisite study. Clin Infect Dis. 2009;48 Suppl 2:S49-56.
Levine OS, T Cherian, R Hajjeh, M Deloria Knoll. Progress and future challenges in coordinated surveillance and detection of pneumococcal and Hib disease in developing countries. Clin Infect Dis. 2009;48 Suppl 2:S33-6.
Shah AS, M Deloria Knoll, PR Sharma, P Kulkarni, JC Moïsi, MK Lalitha, M Steinhoff, K Thomas. Invasive pneumococcal disease in Kanti Children's Hospital, Nepal, as observed by the South Asian Pneumococcal Alliance network. Clin Infect Dis. 2009;48 Suppl 2:S123-8.