PhD, Saint Louis University, 2008
MPH, Saint Louis University, 2007
MA, Boston University, 2002
Dr. Joshu's research focuses on the prevention of colorectal and prostate cancers, including (1) the role of modifiable factors, in particular obesity, on the risk of colorectal and prostate cancer outcomes, and (2) the early detection of these cancers through both established and new modalities. The purpose of her work is to develop prevention strategies, and to translate population-based research into clinically useful tools.
Her work on colorectal cancer explores the association of obesity and diabetes and their metabolic consequences with colorectal cancer and precursor lesions, and informs the prioritization of intervention efforts based on the national prevalences of modifiable risk factors. She also seeks to improve colorectal cancer screening via (1) identifying over or under screened groups, (2) identifying opportunities for quality improvement and quality assurance, and (3) exploring new modalities for screening (e.g. KRAS mutations in circulating blood).
Her work on poor prostate cancer outcomes focuses on identifying biological mechanisms by which modifiable factors may influence recurrence, including studies on prostate tissue-based measures of inflammation, hormones, growth factors, and oxidation. She also seeks to reduce poor prostate cancer outcomes by investigating whether modification of risk factors for chronic disease incidence reduces risk of recurrence after treatment and improving prostate cancer prognostication via the optimization and validation of an independent prognostic tissue biomarker (e.g. telomere length).
Honors and Awards
Delta Omega Honorary Public Health Society, Alpha Delta Chapter
Martin D. Abeloff, MD Scholar-in-Training in Cancer Prevention and Control, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine