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Environmental Health Sciences Faculty Web Site - Brian S. Schwartz, MD, MS
BALTIMORE MEMORY STUDY
Abstract
Publications:
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Baltimore Memory Study Logo |
Brochure/Pamphlet:
Selected Publications:
Schwartz BS, Glass TA, Bolla KI, Stewart WF, Glass G, Rasmussen M, Bressler J, Shi W, Bandeen-Roche K. Disparities in cognitive functioning by race/ethnicity in the Baltimore Memory Study. Environ Health Perspect 2004; 112: 314-320.
Schafer JH, Glass TA, Bressler J, Schwartz BS. Blood lead is a predictor of homocysteine levels in a population-based study of older adults. Environ Health Perspect 2005;113: 31-35.
Schafer JH, Glass TA, Bolla KI, Schwartz BS. Homocysteine and cognitive function in a population-based study of older adults. J Am Geriatrics Soc 2005; in press.
Weil M, Bressler J, Parsons P, Bolla K, Glass TA, Schwartz BS. Blood mercury levels and neurobehavioral function in the Baltimore Memory Study. J Am Med Assoc 2005; submitted.
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Neighborhood Hazard Index and Obesity Map |
FORMER ORGANOLEAD WORKERS STUDY
Phase I
Publications:
Photos:
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Phase II
Publications:
Photos:
Voxel-based morphometry: associations with bone lead concentration - PowerPoint
JPEG: 
Phase III (Pending)
Abstract
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Selected Publications:
Schwartz BS, Bolla KI, Stewart W, Ford DP, Agnew J, Frumkin H. Decrements in neurobehavioral performance associated with mixed exposure to organic and inorganic lead. Am J Epidemiol 1993; 137: 1006-1021.
Schwartz BS, McGrail M, Stewart W, Pluth T. Comparison of measures of lead exposure, dose, and chelatable lead burden after provocative chelation in organolead workers. Occup Environ Med 1994; 51: 669-673.
Balbus-Kornfeld J, Stewart W, Bolla KI, Schwartz BS. Cumulative inorganic lead exposure and neurobehavioral test performance in adults: an epidemiologic review. Occup Environ Med 1995; 52: 2-12.
Bolla KI, Schwartz BS, Stewart W, Rignani J, Agnew J, Ford DP. A comparison of neurobehavioral function in workers exposed to a mixture of organic and inorganic lead and in workers exposed to solvents. Am J Ind Med 1995; 27: 231-246.
McGrail MP, Stewart W, Schwartz BS. Predictors of blood lead levels in organolead manufacturing workers. J Occup Environ Med 1995; 37: 1224-1229.
Mitchell CS, Bolla KI, Shear M, Schwartz BS. Clinical evaluation of 58 organolead manufacturing workers. J Occup Environ Med 1996; 38: 372-378.
Balbus JM, Stewart W, Bolla K, Schwartz BS. Simple visual reaction time in organolead manufacturing workers: comparison of different methods of modeling lead exposure and reaction time. Am J Indus Med 1997; 32: 544-549.
Balbus JM, Stewart W, Bolla K, Schwartz BS. Simple visual reaction time in organolead manufacturing workers: influence of the inter-stimulus interval. Arch Environ Health 1998; 53: 264-270.
Schwartz BS, Stewart WF, Todd AC, Links JM. Predictors of DMSA-chelatable lead levels and bone lead levels in organolead manufacturing workers. Occup Environ Med 1999; 56: 22-29.
Stewart WF, Schwartz BS, Simon D, Bolla KI, Todd AC, Links J. Neurobehavioral function and tibial and chelatable lead levels in 543 former organolead workers. Neurology 1999; 52: 1610-1617.
Schwartz BS, Stewart WF, Kelsey KT, Simon D, Park S, Links JM, Todd AC. Associations of tibial lead levels with BsmI polymorphisms in the vitamin D receptor in former organolead manufacturing workers. Environ Health Perspect 2000; 108: 199-203.
Schwartz BS, Stewart WF, Todd AC, Simon D, Links J. Different associations of blood lead, meso 2,3-dimercaptosuccinic acid (DMSA)-chelatable lead, and tibial lead levels with blood pressure in 543 former organolead manufacturing workers. Arch Environ Health 2000; 55: 85-92.
Schwartz BS, Stewart WF, Bolla KI, Simon D, Bandeen-Roche K, Gordon B, Todd AC, Links JM. Past adult lead exposure is associated with longitudinal decline in cognitive function. Neurology 2000; 55: 1144-1150.
Tassler P, Schwartz BS, Coresh J, Stewart WF, Todd AC. Associations of tibia lead, DMSA-chelatable lead, and blood lead with peripheral nervous system measures in former organolead manufacturing workers. Am J Indus Med 2001; 39: 254-261.
Glenn BS, Stewart WF, Schwartz BS, Bressler J. Relation of alleles of the sodium-potassium adenosine triphosphatase α 2 gene with blood pressure and lead exposure. Am J Epidemiol 2001; 153: 537-545.
| Links JM, Schwartz BS, Simon D, Stewart WF. The influence of toxicant residence time and bioavailability from body stores in estimation of cumulative target organ dose: application to lead-associated neurocognitive decline. Environ Health Perspect 2001; 109: 361-368. |
Characterization of Toxicokinetics and Toxicodynamics with Linear Systems Theory |
Stewart WF, Schwartz BS, Simon D, Kelsey K, Todd AC. ApoE genotype, past adult lead exposure, and neurobehavioral function. Environ Health Perspect 2002;110:501-505.
Glenn BS, Stewart WF, Links JM, Todd AC, Schwartz BS. The longitudinal association of lead with blood pressure. Epidemiology 2003; 14: 30-36.
Ferrer E, Salthouse TA, Stewart WF, Schwartz BS. Modeling age and retest processes in longitudinal studies of cognitive abilities. Psychol Aging 2004; 19: 243-259.
Ferrer E, Salthouse TA, McArdle TJ, Stewart WF, Schwartz BS. Multivariate modeling of age and retest in longitudinal studies of cognitive abilities. Psychology & Aging 2005; submitted.
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Cumulative Lead Dose is Associated with Prevalence & Severity of White Matter Lesions |
KOREA LEAD STUDY
Phase I
Abstract
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Schematic of Worker's Dose Over Time |
Publications:
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Phase II
Abstract
Publications:
Photos:
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Selected Publications:
Lee B-K, Schwartz BS, Stewart W, Ahn K-D. Urinary lead excretion after DMSA and EDTA: evidence for differential access to lead storage sites. Occup Environ Med 1995; 52: 13-19.
Schwartz BS, Lee B-K, Stewart W, Ahn K-D, Springer K, Kelsey K. Associations of δ -aminolevulinic acid dehydratase genotype with plant, exposure duration, and blood lead and zinc protoporphyrin levels in Korean lead workers. Am J Epidemiol 1995; 142: 738-745.
Schwartz BS, Lee B-K, Stewart W, Ahn K-D, Kelsey K, Bressler J. Associations of subtypes of hemoglobin with δ -aminolevulinic acid dehydratase genotype and dimercaptosuccinic acid-chelatable lead levels. Arch Environ Health 1997; 52: 97-103.
Schwartz BS, Lee B-K, Stewart W, Ahn K-D, Kelsey KT. δ -Aminolevulinic acid dehydratase genotype modifies 4-hour urinary lead excretion after oral administration of dimercaptosuccinic acid. Occup Environ Med 1997; 54: 241-246.
Sithisarankul P, Schwartz BS, Lee B-K, Kelsey KT, Strickland PT. Aminolevulinic acid dehydratase genotype mediates plasma levels of the neurotoxin, 5-aminolevulinic acid, in lead-exposed workers. Am J Indus Med 1997; 32: 15-20.
Sithisarankul P, Schwartz BS, Lee B-K, Strickland PT. Urinary 5-aminolevulinic acid (ALA) adjusted by creatinine: a surrogate for plasma ALA. J Occup Environ Med 1998; 40: 901-906.
Lee B-K, Ahn K-D, Lee S-S, Lee G-S, Kim Y-B, Schwartz BS. A comparison of different lead biomarkers in their associations with lead-related symptoms. Int Arch Occup Environ Health 2000; 73: 298-304.
Todd AC, Lee B-K, Lee G-S, Ahn K-D, Moshier EL, Schwartz BS. Predictors of DMSA chelatable lead, tibial lead, and blood lead in 802 Korean lead workers. Occup Environ Med 2001; 58: 73-80.
Schwartz BS, Lee B-K, Lee G-S, Stewart WF, Lee S-S, Hwang K-Y, Ahn K-D, Kim Y-B, Bolla KI, Simon D, Parsons PJ, Todd AC. Associations of blood lead, dimercaptosuccinic acid-chelatable lead, and tibia lead with neurobehavioral test scores in South Korean lead workers. Am J Epidemiol 2001; 153: 453-464.
Lee B-K, Lee G-S, Stewart WF, Ahn K-D, Simon D, Kelsey KT, Todd AC, Schwartz BS. Associations of blood pressure and hypertension with lead dose measures and polymorphisms in the vitamin D receptor and δ -aminolevulinic acid dehydratase genes. Environ Health Perspect 2001; 109: 383-389.
Hwang K-Y, Schwartz BS, Lee B-K, Strickland PT, Todd AC, Bressler JP. Associations of lead exposure and dose measures with erythrocyte protein kinase C activity in 212 current Korean lead workers. Toxicological Sciences 2001; 62: 280-288.
Lee S-S, Lee B-K, Lee G-S, Stewart WF, Simon D, Kelsey K, Todd AC, Schwartz BS. Associations of lead biomarkers and delta-aminolevulinic acid dehydratase and vitamin D receptor genotypes with hematopoietic outcomes in Korean lead workers. Scand J Work Environ Health 2001; 27: 402-411.
Hwang K-Y, Lee B-K, Bressler JP, Bolla KI, Stewart WF, Schwartz BS. Protein kinase C activity and the relations between blood lead and neurobehavioral function in lead workers. Environ Health Perspect 2002; 110: 133-138.
Weaver VM, Lee B-K, Ahn K-D, Lee G-S, Todd AC, Stewart WF, Wen J, Simon DJ, Parsons PJ, Schwartz BS. Associations of lead biomarkers with renal function in Korean lead workers. Occup Environ Med 2003; 60: 551-562.
Weaver BM, Schwartz BS, Ahn K-D, Stewart WF, Kelsey KT, Todd AC, Wen J, Simon DJ, Lustberg ME, Parsons PJ, Silbergeld EK, Lee B-K. Associations of renal function with polymorphisms in the δ-aminolevulinic dehydratase, vitamin D receptor, and nitric oxide synthase genes in Korean lead workers. Environ Health Perspect 2003; 111: 1613-19.
Theppeang K, Schwartz BS, Lee B-K, Lustberg ME, Silbergeld EK, Kelsey KT, Parsons PJ, Todd AC. Associations of patella lead with polymorphisms in the vitamin D receptor, δ-aminolevulinic acid dehydratase and endothelial nitric oxide synthase genes. J Occup Environ Med 2004; 46: 528-537.
Lustberg ME, Schwartz BS, Lee B-K, Todd AC, Silbergeld EK. The G 894-T 894 polymorphism in the gene for endothelial nitric oxide synthase and blood pressure in lead-exposed workers from Korea. J Occup Environ Med 2004; 46: 584-590.
Schwartz BS, Lee B-K Bandeen-Roche K, Stewart WF, Bolla KI, Links J, Weaver V, Todd A. Occupational lead exposure and longitudinal decline in neurobehavioral test scores. Epidemiology 2005; 16: 106-113.
Weaver VM, Jaar BG, Schwartz BS, Todd AC, Ahn K-D, Lee S-S, Wen J, Parsons PJ, Lee B-K. Associations among lead dose biomarkers, uric acid, and renal function in Korean lead workers. Environ Health Perspect 2005; 113: 36-42.
Weaver VM, Lee B-K, Todd AC, Jaar BG, Ahn K-D, Wen J, Shi W, Parsons PJ, Schwartz BS. Associations of patella lead and other lead biomarkers with renal function in lead workers. J Occup Environ Med 2005; in press.
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IN DEVELOPMENT
Obesity and the built environment - Abstract
Solvent neurotoxicity - Abstract
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