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Department of International Health

Jiou Wang



The protein structure of SOD1, in which mutations are linked to the motor neuron degenerative disease ALS; Middle, the large motor neurons are revealed by silver staining in a mouse spinal cord; Bottom, the small (1mm in length) and transparent Caenorhabditis elegans has a simple, yet well-conserved nervous system (green).

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Faculty Search 2010

Jiou Wang

Rank: Assistant Professor
Joined BMB: November 1, 2009
Upbringing: China

Previous Position: Postdoctoral Fellow with Dr. Arthur Horwich, HHMI/Yale University; Dr. David Borchelt, Johns Hopkins University

Research interests: We aim to understand the basic mechanisms of neurodegeneration and protein quality control. Our goal is to describe at the molecular and cellular levels how specific neurons degenerate, how protein folding and misfolding operate in the cell, and how protective systems fail in neurodegenerative diseases. Using molecular, cellular and biochemical approaches, including C. elegans and mice, we are seeking key genes and pathways to better elucidate human neurodegeneration.

“Neurodegeneration is a poorly understood biomedical phenomenon and a major public health challenge in our increasingly aging society. Hopkins is a special place for basic science research that has a bearing on health. Since I was a graduate student here, the excellent academic environment has always excited me.The BMB faculty, students, postdocs and staff are the most supportive colleagues that I have ever seen."
- Jiou Wang

Johns Hopkins University

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