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Center on the Early Life Origins of Disease

 

 
 

Selected Publications from Core Faculty

Reproductive Health and Pregnancy Outcomes

Growth and Development

Pulmonary Function, Respiratory Health, Food Allergy and Related Conditions

Obesity and Metabolic Syndrome

Epigenetics and Early Life Origins of Disease

Prevention of Stroke and Cardiovascular Disease

Osteoporosis

Statistical Methods

Others

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Reproductive Health and Pregnancy Outcomes

  • Ouyang F, Longnecker MP, Venners SA, Johnson S, Korrick S, Zhang J, Xu X, Christian P, Wang M, Wang X. Preconception serum DDT and B-vitamin status: independent and joint effects on women’s reproductive outcomes. AJCN. 2014 Dec;100(6):1470-8. doi: 10.3945/ajcn.114.088377. Epub 2014 Oct 22. JIF: 6.9
  • Wang G, Divall S, Radovick S,  Paige D, Ning Y, Chen Z, Ji Y, Hong X, Walker S, Caruso D, Pearson C, Wang MC, Zuckerman B,  Cheng TL, Wang X (corresponding author). Preterm Birth and Random Plasma Insulin Levels at Birth and in Early Childhood. JAMA 2014; 311(6):587-596 (see editorial comments). JIF: 30.026
  • Parker MG, Ouyang F, Pearson C, Gillman MW, Belfort MB, Hong X, Wang G, Heffner L, Zuckerman B, Wang X. Prepregnancy BMI and risk of preterm birth: Association heterogeneity by preterm subgroups. BMC Pregnancy and Childbirth. 2014;14(153)  JIF: 2.52
  • Chen Z, Myers R, Wei T, Bind E, Kassim P, Wang G, Ji Y, Hong X, Caruso D, Bartell T, Gong Y, Strickland P, Navas-Acien A, Guallar E, Wang X. Placental Transfer and Concentrations of Cadmium, Mercury, Lead, and Selenium in Mothers, Newborns, and Young Children. J Expo Sci Environ Epidemiol. 2014 Apr 23. doi: 10.1038/jes.2014.26. [Epub ahead of print] JIF: 3.187
  • Ouyang F, Parker M, Cerda S, Pearson C, Fu L, Gilman M, Zuckerman B, Wang X. Placental Weight Mediates the Effects of Prenatal Factors on Fetal Growth: the Extent Differs by Preterm Status. Obesity. 2012 Apr 18.
  • Mestan K, Matoba N, Arguelles L, Harvey C, Ernst LM, Farrow K, Wang X. Cord blood 8-isoprostane in the preterm infant. Early Human Development. 2012, 88(8):683–689.
  • Robison RG, Kumar R, Arguelles LM, Hong X, Wang G, Apollon S, Bonzagni A, Ortiz K, Pearson C, Pongracic JA, Bauchner H, Wang X. Maternal Smoking during Pregnancy, Prematurity and Recurrent Wheezing in Early Childhood. Pediatric Pulmonology. 2012, 47(7):666-673.
  • Liu X, Wang G, Hong X, Tsai H, Liu R, Zhang S, Wang H, Pearson C, Ortiz K, Wang D, Hirsch E, Zuckerman B, Wang X. Associations between Gene Polymorphisms in Fatty Acid Metabolism Pathway and Preterm Delivery in a U.S. Urban Black Population. Human Genetics. 2012 Mar;131(3):341-51.
  • Tsai H, Hong X, Chen J, Liu X, Pearson C, Ortiz K, Fu L, Hirsch E, Heffner L, Weeks DE, Zuckerman B, Wang X. Role of African Ancestry and Gene-Environment Interactions in Predicting Preterm Birth. Obstetrics & Gynecology. 2011, 18(5).
  • Kumar P, Venners S, Fu L, Pearson C, Ortiz K, Wang X. Association of antenatal steroid use with cord blood immune biomarkers in preterm births. Early Human Development. 2011; Aug;87(8):559-64.
  • Matoba N, Ouyang F, Mestan K, Porta, N, Pearson C, Ortiz K, Bauchner H, Zuckerman B, Wang X. Cord blood immune biomarkers in small for gestational age births. Journal of Developmental Origins of Health and Disease. Published online: 27 Jan 2011
  • Mestan K, Ouyang F, Matoba N, Pearson C, Ortiz K, Wang X. Maternal obesity, diabetes mellitus, and cord blood biomarkers in large-for-gestational age infants. Journal of Pediatric Biochemistry. Volume 1, Number 3/2010/2011:217-224.
  • Kumar R, Story RE, Pongracic JA, Hong X, Arguelles L, Wang G, Kuptsova-Clarkson N, Pearson C, Ortiz K, Bonzagni A, Apollon S, Fu L, Bauchner H, Wang X. Maternal pre-pregnancy obesity and recurrent wheezing in early childhood. Pediatric Allergy, Immunology, and Pulmonology. 2010 Sept 23(3):183-190.
  • Mestan K, Yu Y, Matoba N, Cerda S, Demmin B, Pearson C, Ortiz K, Wang X. Placental inflammatory response is associated with poor neonatal growth: preterm birth cohort study. Pediatrics. 2010 Apr; 125(4):e891-8.
  • Tsai HJ, Wang X. Association of genetic ancestry with preterm delivery and related traits among African American mothers (Correspondence). American Journal of Obstetrics and Gynecology. 2009 Jul;201(1):94.e1-10.
  • Tsai HJ, Yu Y, Zhang S, Pearson C, Ortiz K, Xu X, Bauchner H, Zuckerman B, Wang X. Association of genetic ancestry with preterm delivery and related traits among African American mothers. American Journal of Obstetrics and Gynecology. 2009 July; 201(1):94.E1-10. Comments and reply: 2010 Jun;202(6):e12-3.
  • Yu Y, Tsai H, Liu X, Mestan K, Zhang S, Pearson C, Ortiz K, Xu X, Zuckerman B, Wang X. The joint association between F5 gene polymorphisms and maternal smoking during pregnancy on preterm delivery. Human Genetics. 2009 Jan;124(6):659-68.
  • Mestan K, Yu Y, Thorsen P, Skogstrand K, Matoba N, Liu X, Kumar R, Hougaard DM, Gupta M, Pearson C, Ortiz K, Bauchner H, Wang X. Cord Blood Biomarkers of the Fetal Inflammatory Response. Journal of Maternal-Fetal & Neonatal Medicine. 2009 May;22(5):379-87.
  • Matoba N, Yu Y, Mestan K, Pearson C, Ortiz K, Porta N, Thorsen P, Skogstand K, Hougaard D, Zuckerman B, Wang X. Differential Patterns of 27 Cord Blood Immune Biomarkers across Gestational Age. Pediatrics. 2009 May;123(5):1320-8.
  • Hollegaard MV, Grove J, Thorsen P, Wang X, Mandrup S, Christiansen M, Norgaard-Pedersen B, Wojdemann KR, Tabor A, Attermann J, Hougaard DM. Polymorphisms in the tumor necrosis factor alpha and interleukin 1-beta promoters with possible gene regulatory functions increase the risk of preterm birth. Acta Obstetricia et Gynecologica. 87(12):1285-1290.
  • Tsai H, Liu X, Mestan K, Yu Y, Zhang S, Fang Y, Pearson C, Ortiz K, Zuckerman B, Bauchner H, Cerda S, Stubblefield P, Xu X, Wang X. Maternal cigarette smoking, metabolic gene polymorphisms, and preterm delivery: new insights on GxE interactions and pathogenic pathways. Human Genetics. 2008;123:359-69.
  • Kumar R, Yu Y, Story RF, Pongracic JA, Gupta R, Pearson C, Ortiz K, Bauchner HC, Wang X. Prematurity, chorioamnionitis and the development of recurrent wheezing: A prospective birth cohort study. Journal of Allergy & Clinical Immunology. Apr 2008;121(4):878-84.e6.
  • Ronnenberg AG, Venners S, Xu X, Chen C, Wang L, Guang W, Huang A, Wang X. Preconception B-Vitamin and Homocysteine status, conception, and early pregnancy loss. American Journal of Epidemiology. 2007 Aug 1;166(3):304-12.
  • Gupta M, Mestan KK, Martin CR, Pearson C, Ortiz K, Fu L, Stubblefield P, Cerda S, Kasznica JM, Wang X. Impact of clinical and histologic correlates of maternal and fetal inflammatory response on gestational age in preterm births. Journal of Maternal, Fetal, and Neonatal Medicine. 2007;20(1):39-46.
  • Ouyang F, Wang X, Arguelles L, Rosul L, Venners SA, Chen C, Hsu Y, Terwedow H, Wu D, Tang G, Yang J, Xing H, Zang T, Wang B, Xu X. Menstrual cycle lengths and bone mineral density: a cross-sectional, population-based study in rural Chinese women ages 30-49 years. Osteoporosis International. 2007;18:221-233.
  • The Institute of Medicine of the National Academies. “Preterm Birth: Causes, Consequences, and prevention”. The National Academies Press, Washington, D.C., 2006. * Wang X served as a committee member and was one of the major contributors to this report.
  • The Institute of Medicine of the National Academies. “Preterm Birth: Causes, Consequences, and prevention”. The National Academies Press, Washington, D.C., 2006. * Wang X served as a committee member and was one of the major contributors to this report.
  • Venners SA, Liu X, Perry M, Korrick S, Li Z, Yang F, Yang J, Lasley B, Xu X, Wang X. Urinary estrogen and Progesterone metabolite concentrations in menstrual cycles of fertile women with non-conception, early pregnancy loss, or clinical pregnancy. Human Reproduction. 2006; 21(9): 2272-2280.
  • Wang L, Feng Y, Zhang Y, Zhou H, Jiang J, Niu T, Wei LJ, Xu Xin, Xu X, Wang X. Prolylcarboxypeptidase gene, chronic hypertension, and risk of preeclampsia. American Journal of Obstetrics and Gynecology. 2006; 195:162-71.
  • Wang L, Wang X, Laird N, Zuckerman B, Stubblefield P, Xu Xin. Polymorphism in maternal LRP8 gene is associated with fetal growth. American Journal of Human Genetics. 2006;78(5):770-7.
  • Perry MJ, Ouyang F, Korrick S, Venners SA, Chen C, Xu X, Lasley B, Wang X. A Prospective Study of Serum DDT and Progesterone and Estrogen Levels Across the Menstrual Cycle in Nulliparous Women of Reproductive Age. American Journal of Epidemiology. 2006;164:1056-1064.
  • Ouyang F, Perry M, Venners SA, Chen C, Wang B, Yang F, Fang Z, Zang T, Wang L, Xu X, Wang X. Serum DDT, age at menarche, and abnormal menstrual cycle length. Occupational and Environmental Medicine. 2005;62:878-884.
  • Venners SA, Korrick S, Xu X, Chen C, Guang W, Huang A, Altshul L, Perry M, Fu L, Wang X. Preconception Serum DDT and Pregnancy Loss: A Prospective Study Using a Biomarker of Pregnancy. American Journal of Epidemiology. 2005;162: 709-716 (see commentary).
  • Chen C, Wang X, Wang L, Yang F, Tang G, Xing H, Ryan L, Lasley B, Overstreet J, Stanford J, Xu X. Effect of environmental tobacco smoke on levels of urinary hormone markers. Environmental Health Perspectives. 2005;113:412-417.
  • Wang L, Wang X, Wang W, Chen C, Ronnenberg A, Guang W, Huang A, Fang Z, Zang T, Wang L, Xu X. Stress and dysmenorrhea: A population based prospective study. Occupational and Environmental Medicine. 2004;61:1021-1026.
  • Ronnenberg AG, Wood RJ, Wang X, Xing H, Chen C, Chen D, Guang W, Huang A, Wang L, Xu X. Preconception hemoglobin and ferritin concentrations are associated with pregnancy outcome in a prospective cohort of Chinese women. Journal of Nutrition. 2004; 134: 2586-91.
  • Hao K, Wang X, Niu T, Xu Xin, Li A, Chang W, Wang L, Li G, Laird N, Xu X. A candidate gene association study on preterm delivery: application of high-throughput genotyping technology and advanced statistical methods. Human Molecular Genetics. 2004;13:683-691.
  • Venners SA, Wang X, Chen C, Wang L, Chen D, Guang W, Huang A, Ryan L, O’Connor J, Lasley B, Overstreet J, Wilcox A, Xu X. Paternal smoking and early pregnancy loss: A prospective study using a biomarker of pregnancy. American Journal of Epidemiology. 2004; 159(10):993-1001.
  • Ronnenberg AG, Wang X, Xing H, Chen C, Chen D, Guang W, Huang A, Wang L, Ryan L, Xu X. Low preconception body mass index is associated with birth outcome in a prospective cohort of Chinese women. Journal of Nutrition. 2003; 133:3449-55.
  • Wang X, Chen C, Wang L, Chen D, Guang W, French J. Conception, early pregnancy loss, and time to clinical pregnancy: a population-based prospective study. Fertility and Sterility. 2003; 79:577-584.
  • Cho S, Wang X. “Reproductive Epidemiology”. In: Abdel H. El-Shaarawi and Walter W. Piegorsch (eds): The Encyclopedia of Environmetrics. Volume 3, p1758-1764. John Wiley & Sons, Ltd, Chichester, 2002.
  • Wang X, Zuckerman B, Pearson C, Kaufman G, Chen C, Wang G, Niu T, Wise P, Bauchner H, Xu X. Maternal cigarette smoking, metabolic gene polymorphism, and infant birth weight. Journal of American Medical Association. 2002; 287:195-202. ().
  • Cho S, Wang X. “Reproductive Epidemiology”. In: Abdel H. El-Shaarawi and Walter W. Piegorsch (eds): The Encyclopedia of Environmetrics. Volume 3, p1758-1764. John Wiley & Sons, Ltd, Chichester, 2002.
  • Venners SA, Wang X, Chen C, Wang B, Ni J, Jin Y, Yang J, Fang Z, Weiss S, Xu X. Exposure-response relationship between paternal smoking and children's pulmonary function. American Journal of Respiratory and Critical Care Medicine. 2001;164:973-6.
  • Chen C, Wang X, Chen D, Li G, Ronnenberg A, Watanabe H, Wang X, Ryan L, Smith T, Christiani, D, Xu X. Tofu consumption and blood lead levels in young Chinese adults. American Journal of Epidemiology. 2001; 153:1206-12.
  • Wang X, Zuckerman B, Kaufman G, Wise P, Hill M, Niu T, Ryan L, Wu D, Xu X. Molecular epidemiology of preterm delivery: methodology and challenges. Paediatric and Perinatal Epidemiology. 2001; 15(suppl 2): 63-77.
  • Chen C, Cho SI, Damokosh AI, Chen D, Li G, Wang X, Xu X. Prospective study of exposure to environmental tobacco smoke and dysmenorrhea. Environmental Health Perspectives. 2000; 108:1019-1022.
  • Chen D, Cho SI, Chen C, Wang X, Damokosh A, Ryan L, Smith T, Christiani D, Xu X. Exposure to benzene, occupational stress, and reduced birth weight. Occupational and Environmental Medicine. 2000; 57:661-667.
  • Wu D, Wang X, Chen D, Niu T, Ni T, Liu X, Xu X. Metabolic gene polymorphisms and risk of dysmenorrhea. Epidemiology. 2000; 11:648-653.
  • Wang X, Chen D, Niu T, Wang Z, Wang L, Ryan L, Smith T, Christiani D, Zuckerman B, Xu X. Genetic susceptibility to benzene and shortened gestation: Evidence of gene-environment interaction (see editorial comments). American Journal of Epidemiology. 2000; 152:693-700.
  • Li G, Jing L, Guo Y, Wang X, Wang H, Liu J, Luo H, Xu Z. A study on environmental lead pollution and blood lead levels in newlywed couples, infants and toddlers in Shenyang. China Public Health. 2000; 16:617-619.
  • Li G, Guo Y, Jing L, Zhang B, Zhao Y, Wang X, Xu Z. A study on relationship between maternal blood lead and IQ scores in infants and toddlers in Shenyang. China Public Health. 2000; 16:390-391.
  • Li G, Wang X, Hu H, Guo Y, Li X, Wang B, Xu X. A study on environmental lead pollution and blood lead levels in newlywed couples, infants and toddlers in Shenyang. Journal of Environment and Health. 1999; 16:103-104, 111.
  • Wang X, Wang M, Niu T, Chen C, Xu X. Microsomal epoxide hydrolase polymorphism and risk of spontaneous abortion. Epidemiology. 1998; 9:540-44.
  • Wang X, Ding H, Ryan L, Xu X. Association between air pollution and low birth weight: A community-based study. Environmental Health Perspective. 1997; 105:514-20.
  • Wang X, Tager IB, VanVunakis H, Speizer FE, Hanrahan JP. Maternal smoking during pregnancy, urine cotinine concentrations, and birth outcomes: A prospective cohort study. International Journal of Epidemiology. 1997; 26:978-88.
  • Xu X, Ding H, Wang X. Acute effects of total suspended particles and sulfur dioxides on preterm delivery: a community-based cohort study. Archives of Environmental Health. 1995;50:407-15. (Journal is continued as: Archives of Environmental and Occupational Health).
  • Wang X, Zuckerman B, Coffman GA, Corwin MJ. Familial aggregation of low birth weight among whites and blacks in the United States. New England Journal of Medicine. 1995; 333:1744-9. (see editorial comments)
  • Wang X, Guyer B, Paige DM. Differences in gestational age-specific birthweight among Chinese, Japanese and White Americans. International Journal of Epidemiology. 1994;23:119-128.
  • Wang X, Strobino DM, Guyer B. Differences in cause-specific infant mortality among Chinese, Japanese, and White Americans. American Journal of Epidemiology. 1992;135:1382-93.
  • Starfield B, Shapiro S, Weiss J, Liang K-Y, Ra K, Paige DM, Wang X. Race, family income, and low birth weight. American Journal of Epidemiology. 1991;134:1167-74.
  • Cherry F, Sandstead H, Rojas P, Johnson L, Batson H, Wang X. Adolescent pregnancy: associations among body weight, zinc nutrition, and pregnancy outcome. American Journal of Clinical Nutrition. 1989; 50:945-54.

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Growth and Development

  • Hong X, Tsai HJ, Liu X, Li Z, Liu X, Tang G, Xing H, Yang J, Wang B, Feng Y, Xu X, Xu X, Wang X. . 2008 Nov;93(11):4511-8.
  • Ouyang F, Lu B, Wang B, Yang J, Li Z, Wang L, Tang G, Xing H, Xu X, Chervin R, Zee P, Wang X. Sleep Patterns among Rural Chinese Twin Adolescents. Sleep Medicine. 2008;(10):479-489.
  • Berkey CS, Wang X, Dockery DW, Ferris BG, Jr. Adolescent height growth of U.S. children. Annals of Human Biology. 1994;21:435-442.
  • Berkey CS, Dockery DW, Wang X, Wypij D, Ferris BG, Jr. Longitudinal height velocity standards for U.S. adolescents. Statistics in Medicine. 1993;12:403-414.

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Pulmonary Function, Respiratory Health, Food Allergy and Related Conditions

  • Hong X, Han K, Ladd-Acosta C, Hansen KD, Tsai H, Liu X, Xu X, Thornton TA, Caruso D, Keet CA, Sun Y, Wang G, Luo W, Kumar R, Fuleihan R, Singh AM, Kim JS, Story RE, Gupta RS, Gao P, Chen Z, Walker SO, Bartell TR, Beaty TH, Fallin MD, Schleimer R, Holt PG, Nadeau KC, Wood RA, Pongracic JA, Weeks DE, Wang X. Genome-wide association study of food allergy identifies peanut allergy-specific loci and evidence of epigenetic mediation in U.S. children. Nature Communications  2015  DOI:10.1038/ncomms7304
  • Warren CM, Gupta RS, Sohn MW, Oh EH, Lal N, Garfield GF, Caruso D, Wang X, Pongracic, JA. Differences in empowerment and quality of life among parents of children with food allergy. Ann Allergy Asthma Immunol  2015; 1-9.
  • Tripathi P, Hong X, Caruso D, Gao P*, Wang X* (co-corresponding authors). Genetic Determinants in the Development of Sensitization to Environmental Allergens in Early Childhood. Immunity, Inflammation and Disease 2014; 2(3):193-204
  • Bousquet J, Gern JE, Martinez FD, Anto JM, Johnson CC, Holt PG, Lemanske RF Jr, Le Souef PN, Tepper R, von Mutius ERM, Arshad SH, Bacharier LB, Becker A, Belanger K, Bergstrom A, Bernstein D, Cabana MD, Carroll KN, Castro M,  Cooper PJ, Gillman MW, Gold DR, Henderson J, Heinrich J, Hong S-J, Jackson DJ, Keil T, Kozyrskyj AL, Lodrup-Carlsen K, Miller RL, Momas I, Morgan WJ, Noel P, Ownby DR, Pinart M, Ryan P, Schwaninger JM, Sears MR, Simpson A, Smit HA, Stern D, Subbarao P, Valenta R, Wang X, Weiss ST, Wood R, Wright AL, Wright RJ, Togias A, Gergen PJ.  Birth cohorts in asthma and allergic diseases:  Report of a NIAID, NHLBI MeDALL joint workshop.  Journal of Allergy & Clinical Immunology. Volume 133, Issue 6, June 2014, Pages 1535–1546.  JIF: 12.047
  • Liu X, Arguelles L, Zhou Y, Wang G, Chen Q, Tsai H, Hong X, Liu R, Price H, Pearson C, Apollon S, Cruz N, Schleimer R, Langman C, Pongracic J, Wang X. Pediatric Research. (in press)
  • Hong X, Xin Liu, Wang X. “Genetics, Epigenetics, and GxE interactions in Food Allergy". Seminars in Immunopathology. 2012.
  • Hong X, Caruso D, Kumar J, Liu R, Liu X, Wang G, Wang X. . Allergy. 2012. Dec;67(12):1538-46.
  • Zhang S, Liu X, Kim JS, Ouyang F, Wang B, Li Z, Tang G, Liu X, Yang J, Xu X, Wang X. Association between short sleep duration and the risk of sensitization to food and aero allergens in Rural Chinese Adolescents. Clinical and Experimental Allergy. 2011 Apr;41(4):547-55.
  • Liu X, Wang GY, Hong XM, Wang D, Tsai HJ, Zhang SC, Arguelles L, Kumar R, Wang HJ, Liu R, Zhou Y, Pearson C, Ortiz K, Schleimer R, Holt R, Pongracic J, Price HE, Langman C, Wang X. Gene-Vitamin D Interactions on Food Sensitization: A prospective birth cohort study. Allergy. 2011 Nov;66(11):1442-8.
  • Hong X, Wang G, Liu X, Kumar R, Tsai H, Arguelles L, Hao K, Pearson C, Ortiz K, Bonzagni A, Apollon S, Fu L, Caruso D, Pongracic J, Schleimer R, Holt P, Bauchner H, Wang X. Gene Polymorphisms, Breastfeeding and Development of Food Sensitization in Early Childhood. Journal of Allergy & Clinical Immunology. 2011 Aug;128(2):374-381.e2.
  • Kumar R, Tsai H, Hong X, Pearson C, Fu M, Pongracic J, Bauchner H, Wang X. African Ancestry, Early Life Exposures, and Respiratory Morbidity in Early Childhood. Clinical and Experimental Allergy. 2011 Sep 25.
  • Kumar R, Tsai HJ, Hong X, Liu X, Wang G, Pearson C, Ortiz K, Fu L, Pongracic J, Bauchner H, Wang X: Race, Ancestry and Development of Food Allergen Sensitization in Early Childhood. Pediatrics. 2011 Oct;128(4):e821-9.
  • Hong X, Tsai HJ, Liu X, Arguelles L, Kumar R, Wang G, Kuptsova-Clarkson N, Pearson C, Ortiz K, Bonzagni A, Apollon S, Fu L, Pongracic JA, Schleimer R, Holt PG, Bauchner H, Wang X. Does genetic regulation of IgE begin in-utero? Evidence from TH1/TH2 gene polymorphisms and cord blood total IgE. Journal of Allergy & Clinical Immunology. 2010;126(5):1059-1067.
  • Springston EE, Shulruff J, Smith B, Wang X, Pongracic J, Holl J, Gupta RS. Variations in quality of life among caregivers of food-allergic children. Annals of Allergy, Asthma & Immunology2010 Oct;105(4):287-294.
  • Gupta RS, Springston EE, Kim JS, Smith B, Pongracic JA, Wang X, Holl J. Food allergy knowledge, attitudes, and beliefs of the primary care physicians. Pediatrics. 2010;125:126-32.
  • Kumar R, Caruso DM, Arguelles L, Kim J, Schroeder A, Rowland B, Meyer KE, Schwartz K, Birne J, Ouyang F, Pongracic JA, Wang X. Early life eczema, food introduction and risk of food allergy in children. Pediatric Allergy, Immunology, and Pulmonology. 2010 Sept;23(3):175-82.
  • Gupta RS, Springston EE, Smith B, Kim JS, Pongracic JA, Wang X, Holl J. Food allergy knowledge, attitudes, and beliefs of parents with food-allergic children in the United States. Pediatric Allergy and Immunology. 2010;21:927-34.
  • Hong X, Tsai HJ, Wang X. “Genetics of Food Allergy”. Current Opinion in Pediatrics. 2009; 21(6):770-776.
  • Kumar R, Ouyang F, Story RE, Pongracic JA, Hong X, Wang G, Pearson C, Ortiz K, Bauchner H, Wang X. Gestational diabetes, atopic dermatitis and allergen sensitization in early childhood. Journal of Allergy & Clinical Immunology. 2009; 124(5):1031-1038.
  • Hong X, Tsai HJ, Wang X. “Genetics of Food Allergy”. Current Opinion in Pediatrics. 2009; 21(6):770-776.
  • Gupta RS, Kim JS, Springston EE, Smith B, Pongracic JA, Wang X, Holl J. Food allergy knowledge, attitudes, and beliefs in the United States. Annals of Allergy, Asthma & Immunology. 2009 Jul;103(1):43-50.
  • Liu X, Zhang SC, Tsai HJ, Hong XM, Wang BY, Fang YP, Liu X, Pongracic J, Wang X. Genetic and Environmental Contributions to Allergen Sensitization in a Chinese Twin Study. Clinical and Experimental Allergy. 2009;39(7):991-998.
  • Hong X, Zhou H, Tsai HJ, Wang X, Liu X, Wang B, Xu X, Xu X. Cysteinyl Leukotriene Receptor 1 Gene Variation and Risk of Asthma in Chinese Population. European Respiratory Journal. 2009 Jan;33(1):42-8.
  • Ouyang F, Kumar R, Pongracic J, Story RE, Liu X, Wang B, Xing H, Liu X, Li Z, Zhang W, Fang Y, Zhang S, Xu X, Wang X. Adiposity, serum lipid levels, and allergic sensitization in Chinese men and women. Journal of Allergy & Clinical Immunology. 2009 April;123(4):940-8.
  • Schroeder A, Kumar R, Pongracic JA, Sullivan CL, Caruso DM, Costello J, Meyer KE, Vucic Y, Gupta R, Kim JS, Fuleihan R, Wang X. Food Allergy is Associated with an Increased Risk of Asthma. Clinical and Experimental Allergy. 2009 Feb;39(2):261-70.
  • Tsai HJ, Kumar R, Pongracic J, Liu X, Story R, Yu Y, Caruso D, Costello J, Schroeder A, Fang Y, Demirtas H, Meyer K, O’Gorman MR, Wang X. Familial Aggregation of Food Allergy and Sensitization to Food Allergens: A Family-Based Study. Clinical and Experimental Allergy. 2009; Jan;39(1):101-9.
  • Kim JS, Ouyang F, Pongracic JA, Fang Y, Wang B, Liu X, Xing H, Caruso D, Liu X, Zhang S, Xu X, Wang X. . Nov; 122(5):929-935.e4.
  • Yu Y, Kumar R, Venners S, Pongracic J, Wang B, Yang J, Li Z, Wang L, Liu X, Tang G, Xing H, Xu X, Wang X. Age and gender specific lung function predictive equations provide similar predictions for both a twin population and a general population from age 6 through adolescence. Pediatric Pulmonology. 2007 Jul;42(7):631-9.
  • Kumar R, Wang B, Wang X, Chen C, Yang J, Fu L, Xu X. Bronchodilator responses in Chinese children from asthma index families and the general population. Journal of Allergy & Clinical Immunology. 2006;117(6):1257-1263.
  • Wang X, Mensinga TT, Schouten JP, Rijcken B, Weiss ST. Determinants of maximally attained level of pulmonary function. American Journal of Respiratory and Critical Care Medicine. 2004; 169:941-949.
  • Xu X, Yang J, Chen C, Wang B, Jin Y, Fang Z, Wang X, Weiss ST. Familial aggregation of pulmonary function in a rural Chinese Community. American Journal of Respiratory and Critical Care Medicine. 1999; 160:1928-1933.
  • Gold DR, Wang X, Wypij D, Speizer FE, Ware JH, Jr, Dockery DW. Effects of cigarette smoking on lung function in adolescent boys and girls. New England Journal of Medicine. 1996; 335:931-7.
  • Gold DR, Wypij D, Wang X, Speizer FE, Pugh M, Ware JH, Ferris BG, Jr, Dockery DW. Gender and race specific effects of asthma and wheeze on level and growth of lung function in children in six U.S. Cities. American Journal of Respiratory and Critical Care Medicine. 1994;149:1198-1208.
  • Wang X, Wypij D, Gold DR, Speizer FE, Ware JH, Ferris BG, Jr, Dockery DW. A longitudinal study of the effects of parental smoking on pulmonary function in children 6-18 years. American Journal of Respiratory and Critical Care Medicine. 1994;149:1420-1425.
  • Wang X, Dockery DW, Wypij D, Gold DR, Speizer FE, Ware JH, Ferris BG, Jr. Pulmonary function growth velocity in children 6 to 18 years of age. American Review of Respiratory Disease. 1993;148:1502-8.
  • Wang X, Dockery DW, Wypij D, Fay ME, Ferris BG, Jr. Pulmonary function between 6 and 18 years of age. Pediatric Pulmonology. 1993;15:75-88.

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Obesity and Metabolic Syndrome

  • Qin X, Li Y, Yuan H, Xie D, Tang G, Wang B, Wang X, Xu X, Xu X, Hou FF. Relationship of MTHFR gene 677C to T polymorphism, homocysteine, and estimated glomerular filtration rate levels with the risk of new-onset diabetes. Medicine 2015 (in press)
  • Liu R, Christoffel KK, Brickman WJ, Liu X, Gadgil M, Wang G, Zimmerman D, Chen Q, Wang B, Li Z, Xing H, Xu X, Wang X.  Do static and dynamic insulin resistance indices perform similarly in predicting pre-diabetes and type 2 diabetes? Diabetes Res Clin Pract. 2014 Apr 30. pii: S0168-8227(14)00197-1. doi: 10.1016/j.diabres.2014.04.014. [Epub ahead of print]  JIF: 3.187
  • Wang G, Divall S, Radovick S,  Paige D, Ning Y, Chen Z, Ji Y, Hong X, Walker S, Caruso D, Pearson C, Wang MC, Zuckerman B,  Cheng TL, Wang X (corresponding author). Preterm Birth and Random Plasma Insulin Levels at Birth and in Early Childhood. JAMA 2014; 311(6):587-596 (see editorial comments). JIF: 30.026
  • Wang G, Chen Z, Bartell T, Wang X. Early Life Origins of Metabolic Syndrome: The Role of Environmental Toxicants. Current Environmental Health Reports. March 2014, Volume 1, Issue 1, pp 78-89
  • Christoffel KK, Wang X, Binns H. “Conference Report: Early Origins of Child Obesity: Bridging Disciplines and Phases of Development”. September 30-October 1, 2010. International Journal of Environmental Research and Public Health. 2012, 9(4), 1227-1262.
  • Liu R, Lui X, Arguelles L, Patwari P, Zee P, Chervin R, Ouyang F, Christoffel K, Wang B, Wang G, Xu X, Wang X. A Population-based twin study on sleep duration and body composition. Obesity (Silver Spring). 2012 Jan;20(1):192-9.
  • Liu R, Brickman W, Christoffel KK, Liu X, Wang G, Arguelles L, Zhang S, Zimmerman D, Wang B, Xu X, Li Z, Xing H, Wang X. Association of Adiposity Trajectories with Insulin Sensitivity and Glycemic deterioration: A Longitudinal Study of Rural Chinese Twin Adults. Diabetes Care. July 2012, 35(7):1506-1512.
  • Wang G, Arguelles L, Liu R, Zhang S, Brickman WJ, Hong X, Tsai HJ, Wang B, Xing H, Li Z, Xu X, Wang X. Tracking Blood Glucose and Predicting Prediabetes in Chinese Children and Adolescents: A Prospective Twin Study. PLoS One. 2011, Dec; 6(12):e28573.
  • Liu R, Zee P, Chervin R, Arguelles L, Birne J, Zhang S, Christoffel K, Brickman W, Zimmerman D, Wang B, Wang G, Xu X, Wang X. Short sleep duration is associated with insulin resistance independent of adiposity in Chinese adult twins. Sleep Medicine. 2011 Oct;12(9):914-9. [This paper won The Elio Lugaresi WASM Award for Sleep Medicine conferred by the World Association of Sleep Medicine and Elsevier Sleep Medicine Sept 2011]
  • Wang G, Christoffel K, Brickman W, Hong X, Arguelles, Zhang S, Wang B, Li Z, Xing H, Tang G, Zimmerman D, Xu X, Wang X. C-Reactive Protein in Adolescent Twins: Patterns and Relationship to Adiposity. Journal of Clinical Endocrinology & Metabolism. October 2011, 96(10).
  • Wang H, Necheles J, Wang B, Birne J, Li Z, Liu X, Tang G, Xu X, Zhang S, Christoffel K, Brickman W, Zimmerman D, Wang X. Association of Adipokines with Blood Pressure in Rural Chinese Adolescents. Journal of Human Hypertension. 2011 Jun 30.
  • Wang H, Zee P, Reid K, Chervin R, Patwari P, Wang B, Li Z, Tang G, Liu X, Yang J, Xu X, Wang X. Gender-specific association of sleep duration with blood pressure in rural Chinese adults. Sleep Medicine. 2011 August; 12(7):693-99.
  • Hong X, Hsu Y, Wang X. Reply to “Fat mass is a positive predictor of bone mass in adolescents.” Journal of Bone and Mineral Research. 2011 Mar;26(3):674-5.
  • Wang G, Wang B, Ouyang F, Liu X, Tang G, Xing H, Li Z, Xu X, Wang X. The patterns of glucose tolerance and insulin resistance among rural Chinese twin children, adolescents, and young adults. Metabolism - Clinical and Experimental. 2010. 59(12):1752-1759.
  • Wang G, Liu X, Christoffel KK, Zhang S, Wang B, Liu R, Li Z, Liu X, Brickman WJ, Zimmerman D, Xu X, Wang X. Prediabetes is not all about obesity: association between plasma leptin and prediabetes in lean rural Chinese Adults. European Journal of Endocrinology. 2010 Aug;163(2):243-9.
  • Zhang S, Liu X, Necheles J, Tsai HJ, Wang G, Wang B, Xing H, Li Z, Liu X, Zang T, Xu X, Wang X. Genetic and environmental influences on serum lipid tracking: A population-based, longitudinal Chinese Twin Study. Pediatric Research. 2010 Oct; 68(4):316-22.
  • Ouyang F, Christoffel KK , Brickman WJ , Zimmerman D, Wang B, Xing H, Zhang S, Arguelles, Wang G, Liu R, Xu X, Wang X. Adiposity is inversely related to insulin sensitivity in relatively lean Chinese adolescents: A population based twin study. American Journal of Clinical Nutrition. 2010; Mar;91(3):662-71.
  • Hong X, Arguelles LM, Tsai H, Zhang S, Wang G, Wang B, Liu X, Li Z, Tang G, Xing H, Xu H, Wang X. Plasma adipokines, bone mass, and hip geometry in rural Chinese adolescents. Journal of Clinical Endocrinology and Metabolism. 2010;95(4):1644-1652.
  • Hong X, Arguelles LM, Liu X, Tsai H, Hsu Y, Wang B, Zhang S, Li Z, Tang G, Liu X, Yang J, Xu X, Langman C, Wang X. Percent fat mass is inversely associated with bone mass and hip geometry in rural Chinese Adolescents. Journal of Bone and Mineral Research. 2010; 25(7):1544-1554.
  • Yu Y, Wang B, Brickman W, Zimmerman D, Li Z; Wang L; Liu X; Tang G; Xing H; Xu X, Wang X: Association of central adiposity with prediabetes and decreased insulin sensitivity in rural Chinese normal-weight and overweight women. Metabolism. 2010; 59:1047–1053.
  • Zhang S, Liu X, Brickman WJ, Christoffel KK, Zimmerman D, Tsai HJ, Wang G, Wang B, Li Z, Tang G, Liu X, Yang J, Xu X, Wang X. Association of plasma leptin concentrations with adiposity measurements in rural Chinese adolescents. Journal of Clinical Endocrinology and Metabolism. 2009;(94)9:3497-3504.
  • Zhang S, Liu X, Yu Y, Hong X, Christoffel KK, Wang B, Tsai HJ, Li Z, Liu X, Tang G, Xing H, Brickman WJ, Zimmerman D, Xu X, Wang X. Genetic and environmental contributions to phenotypic components of metabolic syndrome: A population-based twin study. Obesity. 2009 Aug;17(8):1581-7.
  • Ouyang F, Necheles J, Wang B, Ma W, Li Z, Liu X, Tang G, Xing H, Xu X, Venners SA, Brickman WJ, Christoffel KK, Zimmerman D, Wang X. Association of surrogate and direct measures of adiposity with risk of metabolic syndrome in rural Chinese women. European Journal of Nutrition. 2009;48(6):323-332.
  • Arguelles LM, Langman CB, Ariza AJ, Ali FN, Dilley K, Price H, Liu X, Zhang S, Hong X, Wang B, Xing H, Li Z, Liu X, Zhang W, Xu X, Wang X. Heritability and environmental factors affecting vitamin D status in rural Chinese adolescent twins. Journal of Clinical Endocrinology and Metabolism. 2009 Sep;94(9):3273-81.
  • Feng Y, Mao G, Ren X, Xing H, Tang G, Li Q, X Li, Sun L, Yang J, Ma W, Wang X, Xu X. Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients. Diabetes Care. Oct;31(10):1939-44.
  • Mao G, Hong X, Xing H, Liu P, Liu H, Yu Y, Zhang S, Jiang S, Wang X, Xu X. Efficacy of folic acid and enalapril combined therapy on reduction of blood pressure and plasma glucose: A multicenter, randomized, double-blind, parallel-controlled clinical trial. Nutrition. 2008 Nov-Dec;24(11-12):1088-96.
  • Wang H, Necheles J, Carnethon M, Wang B, Li Z, Wang L, Liu X, Yang J, Tang G, Xing H, Xu X, Wang X. Adiposity measures and blood pressure in Chinese children and adolescents. Archives of Diseases of Children. 2008;93;738-744.
  • Wang B, Necheles J, Ouyang F, Ma W, Li Z, Liu X, Yang J, Xing H, Xu X, Wang X. Monozygotic co-twin analyses of body composition measurements and serum lipids. Preventive Medicine. 2007 Nov;45(5):358-65.
  • Arguelles L, Wang X, Wang B, Demirtas H, Yang J, Li Z, Wang L, Liu X, Tang G, Xing H, Xu X. Body mass index, percent body fat, and bone mass in a cohort of Chinese twins aged 6 to 18 years. Archives of Osteoporosis.Published online: 13 October 2007.
  • Yu Y, Lu BS, Wang B, Wang H, Yang J, Li Z, Wang L, Liu X, Tang G, Xing H, Xu X, Zee PC, Wang X. Short sleep duration and adiposity in Chinese adolescents. Sleep. 2007;30(12):1688-1697.
  • Wang H, Story RE, Venners SA, Wang B, Yang J, Li Z, Wang L, Liu X, Tang, G, Xing H, Xu X, Wang X. Patterns and interrelationships of body fat measures among rural Chinese children aged 6-18 years. Pediatrics. 2007 Jul;120 (1):e94-e101.
  • Perry MJ, Ouyang F, Venners SA, Korrick S, Venners S, Altshul L, Xu X, Wang X. Body mass index and serum 1,1,1-trichloro -2,2-bis (p-chlorophenyl) ethane in nulliparous Chinese women. Cancer Epidemiology, Biomarkers and Prevention. 2005;14:2433-8.

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Epigenetics and Early Life Origins of Disease

  • Wang G, Walker S, Hong X, Bartell T, Wang X. “Epigenetics and Early Life Origins of Chronic Diseases”. Journal of Adolescent Health, 2013; 52 (2S2):S14-21.
  • Wang D, Liu X, Zhou Y, Xie H, Hong X, Tsai HJ, Wang G, Liu R, Wang X. Individual variation and longitudinal pattern of genome-wide DNA methylation from birth to the first two years of life. Epigenetics. 2012 Jun 1;7(6)
  • Hong X, Xin Liu, Wang X. “Genetics, Epigenetics, and GxE interactions in Food Allergy". Seminars in Immunopathology. 2012.
  • Christoffel KK, Wang X, Binns H. “Conference Report: Early Origins of Child Obesity: Bridging Disciplines and Phases of Development”. September 30-October 1, 2010. International Journal of Environmental Research and Public Health. 2012, 9(4), 1227-1262.

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Prevention of Stroke and Cardiovascular Disease

  • Wang Q, Xie, D, Xu X, Qin X, Tang G, Wang B, Wang Y, Hou F, Xu X, Wang X. Blood pressure and renal function decline: a 7-year prospective cohort study in middle-aged rural Chinese men and women.  J Hypertens. 2015 Jan;33(1):136-43. doi: 10.1097/HJH.0000000000000360.
  • Zheng M, Xu X, Wang X, Huo Y, Xu X, Qin X, Tang G, Xing H, Fan F, Cui W, Yang X.  Age, arterial stiffness, and components of blood pressure in Chinese adults. Medicine  2014 Dec;93(29):e262. doi: 0.1097/MD.0000000000000262.
  • Zheng M, Huo Y, Wang X, Xu X, Qin X, Tang G, Xing H, Fan F, Li J, Zhang Y, Wang B, Xu X, Yang X, Chen Y, Qian G. A prospective study on pulse wave velocity (PWV) and response to anti-hypertensive treatments: PWV determines BP control.  Int J Cardiol. 2014 Oct 22;178C:226-231. doi: 10.1016/j.ijcard.2014.10.049. [Epub ahead of print]
  • Qin X, Fan F, Chen F, Chen Y, Cheng X, Cui Y, Zhang Y, Li J, Xu X, Xu X, Huo Y, Wang X. Folic Acid Supplementation with and without vitamin B6 and Revascularization Risk: A Meta-Analysis of Randomized Controlled Trials   Clin Nutr. 2014 Aug;33(4):603-12. JIF: 4.581
  • Qin X, Huo Y, Xie D, Hou F, Xu X, Wang X. Homocysteine-lowering therapy with folic acid is effective in cardiovascular disease prevention in patients with kidney disease: a meta-analysis of randomized controlled trials. Clinical Nutrition. 2012 Dec 28. pii: S0261-5614(12)00280-4.
  • Qin X, Cui Y, Shen L, Sun N, Zhang Y, Li J, Xu X, Wang B, Xu X, Huo Y, Wang, X. Folic acid supplementation and cancer risk: a meta-analysis of randomized controlled tirals. International Journal of Cancer. 2013 Jan 22.
  • He M, Qin X, Cai Y, Sun L, Xu X, Wang B, Tang G, Xing H, Wang X, Xu X, Xu X, Huo Y. Unrecognized lower extremity peripheral arterial disease prevalence and the associated factors in Chinese hypertensive adults. American Journal of Cardiology. 2012 Dec 1; 110(11):1692-8.
  • Qin X, Cai Y, He M, Sun L, Fu J, Zhang Y, Li J, Wang B, Xing H, Tang G, Wang X, Xu X, Xu X, Huo Y. Prevalence of obesity, abdominal obesity and the associated factors in hypertensive adults aged 45 to 75 years. Clinical Nutrition. 2012 Aug 21; pii: s0261-5614(12)00172-0.
  • Qin X, Li J, Zhang Y, Ma W, Fan F, Wang B, Xing H, Tang G, Wang X, Xu X, Xu X, Huo Y. Prevalence and associated factors of diabetes and impaired fasting glucose in Chinese hypertensive adults aged 45 to 75 years. PLoS One. 2012;7(8):e42538.
  • Huo Y, Qin X, Wang J, Sun N, Zeng Q, Xu X, Liu L, Xu X, Wang X. Efficacy of Folic Acid Supplementation in Stroke Prevention: New Insight from a Meta-analysis. International Journal of Clinical Practice. 66 (6), 544-551.
  • Qin X, Li J, Cui Y, Liu Z, Zhao Z, Ge J, Guan D, Hu J, Wang Y, Zhang F, Xu X, Wang X, Xu X, Huo Y. MTHFR C677T and MTR A2756G Polymorphisms and the Homocysteine Lowering Efficacy of Different Doses of Folic Acid in Hypertensives Chinese Adults. Nutrition Journal. 2012 Jan 10;11:2.
  • Qin X, Li J, Cui Y, Liu Z, Zhao Z, Ge J, Guan D, Hu J, Wang Y, Zhang F, Xu X, Wang X, Xu X, Huo Y. Effect of folic acid intervention on ALT concentration in hypertensives without known hepatic disease: a randomized, double-blind, controlled trial. European Journal of Clinical Nutrition. 2012; 66:541-548.
  • Qin X, Xu M, Zhang Y, Li J, Xu X, Wang X, Xu X, Huo Y. Effect of folic acid supplementation on the progression of carotid intima-media thickness: A meta-analysis of randomized controlled trials. Atherosclerosis. 2012; 222:307-313.
  • Qin X, Li J, Cui Y, Liu Z, Zhao Z, Ge J, Guan D, Hu J, Wang Y, Zhang F, Xu X, Wang X, Xu X, Huo Y. Effect of Folic Acid Intervention on the Change of Serum Folate Level in Hypertensive Chinese Adults: Do MTHFR and MTR Gene Polymorphisms Affect Therapeutic Responses? Pharmacogenetics and Genomics. 2012; 22:421-428.
  • Jiang S, Hsu S, Venners S, Zhang Y, Xing H, Wang X, Xu X. Interactive effect of Angiotensin II Type 1 Receptor (AGT1R) polymorphisms and plasma Irbesartan concentration on antihypertensive therapeutic responses to Irbesartan. Journal of Hypertension. 2011 May;29(5):890-5.
  • Qin X, Huo Y, Langman CB, Hou H, Chen Y, Matossian D, Xu X, Wang X. Folic Acid Therapy and Cardiovascular Disease in ESRD /ACKD: A Meta-Analysis. Clinical Journal of the American Society of Nephrology. 2011; 6:482-488.
  • Arguelles LM, Liu X, Venners SA, Ronnenberg AG, Li Z, Yang F, Yang J, Xu X, Wang X. Serum folate and DDT isomers and metabolites are inversely associated in Chinese women: a cross-sectional analysis. Journal of the American College of Nutrition. 2009 Aug;28(4):380-7.
  • Wang X, Qin X, Demirtas H, Xu X. Efficacy of folic acid supplementation in stroke prevention: A meta-analysis (correspondence). Lancet. 2007;370:651.
  • Wang X, Qin X, Demirtas H, Li J, Mao G, Huo Y, Sun N, Liu L, Xu X. Efficacy of folic acid supplementation in stroke prevention: a meta-analysis. Lancet. 2007; 2;369(9576):1876-1882(see editorial comments).
  • Peng S, Yu Y, Hao K, Xing H, Li D, Chen C, Huang A, Hong X, Fang Y, Zhang Y, Li J, Wang B, Wu D, Wang X, Xu X. Heart rate-corrected QT interval duration is significantly associated with blood pressure in Chinese hypertensives. Journal of Electrocardiology. 2006; Apr;39(2):206-10.
  • Wang X, Demirtas H, Xu X. Homocysteine, B Vitamins, and cardiovascular disease. New England Journal of Medicine. 2006;355(2):205-211.
  • Jiang S, Hsu YH, Niu T, Xu X, Xing H, Chen C, Wang X, Zhang Y, Peng S, Xu X. A common haplotype on methylenetetrahydrofolate reductase gene modifies the effect of angiotensin-converting enzyme inhibitor on blood pressure in essential hypertension patients--a family-based association study. Clinical and Experimental Hypertension. 2005 Aug;27(6):509-21.
  • Jiang S, Mao G, Zhang S, Hong X, Tang G, Li Z, Liu X, Zhang Y, Wang B, Xu X, Wang X. Individual and joint association of α1A-Adrenergic receptor Arg347Cys polymorphism and plasma Irbesartan concentration with blood pressure therapeutic response in Chinese hypertensive subjects. Clinical Pharmacology and Therapeutics. 2005;78(3):239-48.
  • Li J, Wang X, Huo Y, Niu T, Chen C, Zhu G, Huang Y, Chen D, Xu X. PON1 polymorphism, diabetes mellitus, obesity, and risk of myocardial infarction. Modifying effect of diabetes mellitus and obesity on the association between P0N1 polymorphism and myocardial infarction. Genetics in Medicine. 2005;7:58-63.
  • Huang G, Xing H, Hao K, Peng S, Wu D, Guang W, Huang A, Hong X, Wang Y, Feng Y, Zhang Y, Li J, Chen C, Wang B, Zhang X, Li D, Yu Y, Liu J, Zhu G, Huo Y, Chen D, Hou Y, Wang X, Xu X, Niu T, Xu X. Beta2 adrenergic receptor gene Arg16Gly polymorphism is associated with therapeutic efficacy of benazepril on essential hypertension in Chinese. Clinical Experimental Hypertension. 2004;26(6):581-92.
  • Zhang Y, Zhang M, Niu T, Xu X, Zhu G, Huo Y, Chen C, Wang X, Xing H, Peng S, Huang A, Hong X, Xu X. D919G polymorphism of methionine synthase gene is associated with blood pressure response to benazepril in Chinese hypertensive patients. Journal of Human Genetics. 2004;49:296-301.
  • Li J, Wang X, Chen C, Xu X, Hong X, Xu X, Gao W, Huo Y. The association between paired basic amino acid cleaving enzyme 4 gene haplotype and diastolic blood pressure. Chinese Medical Journal. 2004;117(3):382-388.
  • Wang X, Wang B, Chen C, Yang J, Fang Z, Zuckerman B, Xu X. Familial aggregation of blood pressure in a rural Chinese community. American Journal of Epidemiology. 1999; 149:412-420.
  • Wang X, Wang B, Zhang F, Chen C, Yang J, Fang Z, Zhang X, Christiani DC, Weiss ST, Zuckerman B, Xu X. Blood pressure at age 3-24 years in a rural community in Anhui, China. Annals of Epidemiology. 1998; 8: 514-12.

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OSTEOPOROSIS

  • Arguelles LM, Ouyang F, Wang X. “Bone Growth Patterns in Rural Chinese Children and Adolescents”. In: Handbook of Growth and Growth Monitoring in Health and Disease. Victor R. Preedy (eds). Springer, 2011.
  • Ouyang F, Wang B, Arguelles LM, Xu X, Yang J, Li Z, Wang L, Liu X, Tang G, Xing H, Langman C, Wang X. Bone growth patterns in Chinese children and adolescents: a 6-year follow-up study provides evidence for sexual dimorphism and tracking. Archives of Osteoporosis. Vol. 2(1-2):29-43. Published online: 30 November 2007.

Statistical Methods

  • Hao K, Wang X. Incorporating individual error rate into association test of unmatched case-control design. Human Heredity. 2004;58:154-63
  • Hao K, Xu X, Laird N, Wang X, Xu X. Power estimation of multiple SNP association test of case-control study and application. Genetic Epidemiology. 2004; 26:22-30

OTHERS

  • Liu H, Liu P, Mao G, Chen G, Wang B, Qin X, Na Y, Liu Z, Wang X, Xu X. Efficacy of combined Amlodipine/Terazosin therapy in male hypertensive patients with lower urinary tract symptoms: a randomized, double-blind clinical trial. Urology. 2009; 74(1):130-136.

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