Applications of the Case-Control Method
June 27 - July 1, 2016
1:30 p.m. – 5:00 p.m.
Course Number: 340.605.11
Following a review of the basic strengths and problems of the case-control method, the course will examine the application of this popular method of investigation. Its use will be discussed in evaluation of risk factors, interventions, and as a surveillance tool. The course format will be based on lectures and lab work. Prerequisites: Completion of basic courses in epidemiology and biostatistics.
- Describe the case-control study paradigm in relation to other observational epidemiologic designs
- Define the criteria for case and control selection in a case-control study
- Distinguish between the various exposure measurement approaches used in case-control studies
- Conduct the appropriate analysis of case-control data
- Properly interpret the results of case-control studies in the context of causal pathways.
Sample Course Readings:
- Buchholz U et al. German Outbreak of Escherichia coli O104:H4 Associated with Sprouts. NEJM, 2011; 365: 1763-70
- Grimes DA et al. Compared to what? Finding controls for case-control studies. Lancet, 2005; 365:1429-33.
- Hayden GF et al. The Case-Control Study: A Practical Review for the Clinician. JAMA, 1982; 247: 326-331.
- Schulz KF et al. Case-control studies: research in reverse. Lancet, 2002; 359: 431-34.
Student Evaluation: Exam
Prerequisite: Basic biostatistics and epidemiology
Grading Restriction: Letter Grade or Pass/Fail