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Biochemistry & Molecular Biology

PhD Thesis Defenses

2014-2015

June 25, 2015
Katherine Reiter
"Wrestling with Malaria characterizing SUMOylation in Plasmodium falciparum "
Advisor: Dr. Michael Matunis 

June 10, 2015
Casey Daniels
"Mass spectrometry based proteomics for the study of ADP-Ribosylation"
Advisor: Dr. Anthony Leung 

December 16, 2014
Hyo Lee
"Cytoskeletal regulation of cortical mechanics in mammalian eggs"
Advisor: Dr. Janice Evans 

October 31, 2014
Mindy Graham
"Targeting the human androgen receptor gene with platinated triplex-forming oligonucleotides"
Advisor: Dr. Paul Miller 

August 6, 2014
Lauren Matthews
"Cell Cyrcle Regulation During Mammalian Female Meiosis Characterization of the MASTL-ENSA/ARPP19 Pathway in Mouse Oocytes"
Advisor: Dr. Janice Evans

July 30, 2014
Xia Feng
"Roles of Disulfide Bonding In the Assembly, Organization, and Dynamics of Keratin Intermediate Filaments in Epidermal Keratinocytes"
Advisor: Dr. Pierre Coulombe

2013-2014

February 21, 2014
David Alvarado
"Assessing the Contribution of Self-Organization of Keratin Interniadiate Filaments to their Biological Functions In Vivo"
Advisor: Dr.  Pierre Coulombe

December 18, 2013
Margaret Dayhoff-Brannigan
"Identifying Novel Genes Involved in Amino Acid Sensing."
Advisor: Dr. Marie Hardwick

December 17, 2013
Ulli Hain
"Autophagy in Plasmodium? Insights, Intrigue, and Inhibition."
Advisor: Dr.  Jürgen Bosch

September 23, 2013
Caelin Potts
"Characterizing the Roles of Sumoylation in Mitosis through Substrate Identification and an Analysis of the SUMO Isopeptidases, SENP1 and SENP2."
Advisor: Dr. Michael Matunis

September 6, 2013
Allen Baron
"The Dual Nature of Reactive Oxygen Species: Regulation of pH Homeostasis and Survival in Saccharomyces Cerevisiae by ROS Damage and Signaling."
Advisor: Dr. Valeria Cullota

2012 - 2013

July 19, 2012
Stephen Slocum
"The Impact of Amplified Nrf2 Signaling on Liver Regeneration and High Fat Diet-Induced Obesity"
Advisor: Dr. Thomas Kensler

February 5, 2012
Teegan Delli-Bovi
"Cofactor Metabolism in Malaria Parasites"
Advisor: Dr. Sean Prigge

November 1, 2012
Jolyn Gisselberg
"Iron Sulfur Cluster Metabolism in the Apicoplast
and Plasmodium falciparum"
Advisor: Dr. Sean Prigge

October 26, 2012
Heather Newman
"Characterizing SUMO function in Saccharomyces cerevisiae
using a versatile library of synthetic mutants"
Advisor: Dr. Michael Matunis

October 11, 2012
Xiaoou Pan
"Regulation of skin keratin by site-specific phosphorylation"
Advisor: Dr. Pierre Coulombe

August 22, 2012
Matthew Beattie
"Redox Biology and the Aging Leydig Cell"
Advisor: Dr. Barry Zirkin

August 1, 2012
Juliane Lessard
"The perception of danger: Keratin 16 regulates alarmin expression
in response to epidermal barrier challenges"
Advisor: Dr. Pierre Coulombe

July 23, 2012
Brian Roelofs
"Post-Translational Modification of Bcl-xL Orchestrates
Non-Canonical Functions"
Advisor: Dr. J. Marie Hardwick

March 6, 2012
Jianmei Zhu
"Regulation and Function of BLM SUMOylation During DNA
Damage Response"
Advisor: Dr. Michael Matunis

2011 - 2012

September 14, 2011
Jeremy Rotty
"Keratin 6 regulates Src activity: Implications for cell biology, wound
healing, and tumorigenesis"
Advisor: Dr. Pierre Coulombe

September 13, 2011
Abena S. Agyeman
"Establishing Candidate Biomarkers to Determine the
Pharmacodynamic Action of Sulforaphane in the Breast"
Advisor: Dr. Thomas Kensler

2010 - 2011

May 31, 2011
Erin L. Stanley
"Leydig cell stem/progenitor cells in neonatal, adult
and aged testes"
Advisor: Dr. Barry Zirkin

February 11, 2011
Ronald J. Stamper
"Regulation of the Biosynthesis of Glycosylphosphatidyl lnositol
Anchors in Saccharomyces cerevisiae by the small G-protein Ras2"
Advisor: Dr. Valeria Culotta

December 10, 2010
Sara E. Beese
"Regulation of the Fps1 glycerol channel in
Saccharomyces cerevisiae"
Advisor: Dr. David Levin

December 3, 2010
Patrick G. Shaw
"Proteomic Profiling of Epigenetic Signaling and Malignant
Progression in Breast Cancer"
Advisor: Dr. Nancy Davidson

October 7, 2010
Jacqueline D. Goeres
"Investigating the Dynamic Interactions of SENP2 at Nuclear
Pore Complexes and Kinetochores"
Advisor: Dr. Michael Matunis

September 14, 2010
Erica Hlavin Bell
"Effects of Cross-link Structure on Replication-independent
DNA Interstrand Cross-link Repair in Mammalian Cells"
Advisor: Dr. Paul Miller

September 3, 2010
Michael Smeaton
"Interstrand cross-links are repaired in adistortion-dependent manner"
Advisor: Dr. Paul Miller