Mathuram Santosham

Mathuram Santosham

  • Director, Health Systems Program

  • Director, Center for American Indian Health

  • Professor, International Health and Pediatrics

  • Departmental Affiliation(s):

    Population, Family and Reproductive Health (Joint)
    Epidemiology (Joint)
    International Health (Primary)
    Division: Health Systems

    Contact Information

    621 N. Washington Street
    Room E8132
    Baltimore , Maryland   21205



    MPH, Johns Hopkins Bloomberg School of Public Health, 1975
    MD, Madras University, 1970


    Epidemiologic studies of enteric infections; improved oral rehydration therapy; field testing of vaccines; h. influenzae type b and pneumococcal infections; neonatal health.

    Honors and Awards

    January 2014- Sabin Gold Medal Award January 1988 -Thrasher Research Fund Award, "In recognition of excellence in research" 1981-1986 - Indian Health Service Award for outstanding dedication and contribution to improving the health of the White Mountain Apache People

    Research Interests

    International Health Epidemiologic studies of enteric infections improved oral rehydration therapy field testing of vaccines h. influenzae tybe b pneumococcal neonatal health Zinc supplementation


    • Coles CL, Bose A, Moses PD, Mathew L, Agarwal I, Mammen T, Santosham M. Infectious etiology modifies the treatment effect of zinc in severe pneumonia. Am J Clin Nutr. 2007; 86: 397-403.
    • Millar EV, O’Brien KL, Bronsdon MA, Madore D, Hackell J, Reid R, Santosham M. Anti-capsular serum antibody concentration and protection against pneumococcal colonization induced by 7-valent conjugate pneumococcal vaccine (PnCRM7). Clin Infect Dis. 2007;44(9):1173-9. PMID 17407035
    • Lipsitch M, O’Neill K, Bugalter B, Trzcinski K, Cordy D, Thompson CM, Goldstein R, Pelton S, Huot H, Bouchet V, Reid R, Santosham M, O’Brien KL. Strain characteristics of Streptococcus pneumoniae isolated from carriage and invasive disease during a cluster-randomized clinical trial of the 7-valent pneumococcal conjugate vaccine. J Infect Dis. In Press.
    • Basset A, Trzcinxki K, Hermos C, O’Brien KL, Reid R, Santosham M. McAdam A, Lipsitch M, Malley R. Frequency of the pilus in pneumococcal isolates: Association with certain capsular serotypes but not with increased virulence. J Clin Microbiol 2007 Mar 28 (E-pub) PMID 17392439
    • Eick A, Shaw J, Thumar B, Reid R, Santosham M, Karron R, O’Brien KL. The role of RSV neutralizing antibodies in protecting infants from severe and non-severe RSV disease. Pediatr Infect Dis J. In Press.