Arthur Dannenberg

Professor

Departmental Affiliation(s):

Molecular Microbiology and Immunology (Joint)
Epidemiology (Joint)
Environmental Health Sciences (Primary)

Contact Information

615 N. Wolfe Street
Room W4001
Baltimore , Maryland   21205
US        

410-377-7125
410-955-0105

Education

MD, Harvard University, 1947
PhD, University of Pennsylvania, 1952
MA, University of Pennsylvania, 1951

Overview

Tuberculosis. Our participation in research concerns pulmonary tuberculosis produced by aerosolized virulent bacilli in the rabbit model: Prevention, with new and old vaccines, and therapy with drugs to prevent liquefaction and cavity formation in this disease. This research involves a thorough gross- and histo-pathological study of the effects of the vaccines and drugs on this disease. My laboratory is now closed. I advise other laboratories on this type of research.

Honors and Awards

Delta Omega Public Health Honorary Society, Alpha Chapter (elected 1983); Society for Leukocyte Biology, Honorary Life Membership (awarded 1984). Special guest lecture, Inflammation Society of Japan, Tokyo, July 1990 School of Hygiene Dean's Lecture, 1/10/91 JHU Immunology Council lecture, 10/8/92 The Pathogenesis of Tuberculosis: A Symposium in Honor of Arthur M. Dannenberg, Jr., at JHSPH 10/6/2004. Listed in: American Men and Women of Science; Who's Who.

Research Interests

tuberculosis BCG sulfur mustard cytokines adhesion molecules allergic dermatitis macrophages and lymphocytes cell mediated immunity CMI delayed-type hypersensitivity DTH

Publications

  • 1. Dannenberg AM Jr. (2006) Pathogenesis of Human Pulmonary Tuberculosis: Insights from the Rabbit Model. ASM Press, Washington, DC.
  • 2. Manabe YC, Dannenberg AM Jr. (2006) Pathophysiology: Basic aspects. I. Pathogenesis of tuberculosis. II. Immunology of tuberculosis. In Schlossberg D, ed. Tuberculosis and Nontuberculous Mycobacterial Infections, Fifth Edition. McGraw-Hill, New York. pp. 18-51.
  • 3. Dorman SE, Hatem CL, Tyagi S, Aird K, Lopez-Molina J, Pitt MLM, Zook BC, Dannenberg AM Jr, Bishai WR, Manabe YC. (2004) Susceptibility to tuberculosis: Clues from studies with inbred and outbread New Zealand White rabbits. Infect Immun 72: 1700-1705.
  • 4. Dannenberg AM Jr. (2003) Macrophage turnover, division and activation within developing, peak and “healed” tuberculous lesions produced in rabbits by BCG. Tuberculosis 83: 251-260.
  • 5. Manabe YC, Dannenberg AM Jr, Tyagi S, Hatem CL, Yoder M, Woolwine SC, Zook BC, Pitt MLM, Bishai WR. (2003) Different strains of Mycobacterium tuberculosis cause various spectrums of disease in the rabbit model of tuberculosis. Infect Immun 71: 6004-6011.