415.671.92 DEVELOPMENTAL BIOLOGY AND HUMAN MALFORMATIONS II

Familiarizes students with modern developmental biology and the use of this knowledge to understand common human malformations. Includes lectures on the methodology and model systems of developmental biology; a review of preimplantation development and gastrulation, and embryogensis/organogensis. Subsequent lectures focus on the development of organ systems.

After successful completion of this course, you will be able to (1) explain the different ways to analyze birth defects: analytically, embryologically, and by developmental biological analysis; (2) describe the basic stages of development: preimplantation, gastrulation, organogenesis, and fetal growth; (3) describe the basic genetic molecular control mechanisms of development; (4) describe the basic concept of evolutionary conservation of ontogeny; (5) define the concepts of homologous genes and structures; (6) describe the mechanism of laterality determination in vertebrates; and (7) analyze a congenital anomaly including the embryology and developmental biology of the genesis of the abnormality using sources including appropriate textbooks, journal articles and online resources.