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340.706.11 METHODS AND APPLICATIONS OF COHORT STUDIES

Department: Epidemiology
Term: Summer Inst. term
Credits: 2 credits
Contact: Alison Abraham
Academic Year: 2012 - 2013
Course Instructor:
Description:

Discusses definition and basic characteristics of cohort studies; graphical methods in epidemiology; methods to estimate and compare incidence rates, including Poisson regression; methods for the analysis of disease-free and survival times; estimation and testing of relative hazards (Cox regression) and of relative times (parametric regression); regression trees for the analysis of prognostic markers; parametric survival analysis and taxonomy of hazards functions using generalized gamma models; methods to nest case-control and case-cohort designs in cohort studies; random effects models for longitudinal data; and the role of cohort studies in evaluating interventions and in guiding public policy. Methods will be illustrated using cohort studies in which faculty have been directly involved. Prerequisite: Intermediate-level courses in both epidemiology and biostatistics and some familiarity with data analysis software packages.

Learning Objective(s):
Upon successfully completing this course, students will be able to:
Describe the principles for the design and conduct of cohort studies
Estimate and compare incidence rates, and times-to-event via relative hazards and relative times
Apply analytic methods to data from large, long-term and multicenter cohort studies coordinated by the instructors’ research team
Appreciate the role of cohort studies for the characterization of natural history of diseases; for evaluation of interventions and for guiding public policy

Methods of Assessment: quizzes and final exam
Location: East Baltimore
Class Times:
  • Mon 06/25/2012 - Fri 06/29/2012
  • Monday 1:30 - 5:00
  • Tuesday 1:30 - 5:00
  • Wednesday 1:30 - 5:00
  • Thursday 1:30 - 5:00
  • Friday 1:30 - 5:00
Enrollment Minimum: 10
Instructor Consent: No consent required
Prerequisite:

Intermediate-level courses in both epidemiology and biostatistics and some familiarity with data analysis software packages.

Auditors Allowed: No
Grading Restriction: Letter Grade or Pass/Fail
Special Comments: Students who have successfully completed 340.728: Methods and Applications of Cohort Studies should not enroll in this course