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Course Catalog

340.670.11 GENETIC EPIDEMIOLOGY IN POPULATIONS

Department:
Epidemiology
Term:
Summer Inst. term
Credits:
2 credits
Academic Year:
2013 - 2014
Location:
East Baltimore
Dates:
Mon 06/10/2013 - Fri 06/14/2013
Class Times:
  • M Tu W Th F,  9:00am - 12:20pm
Auditors Allowed:
No
Grading Restriction:
Letter Grade or Pass/Fail
Contact:
Ayesha Khan
Course Instructors:

Course Evaluation

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Prerequisite:

Basic knowledge of epidemiology and biostatistics

Description:

This course will cover designs and methods for genetic epidemiology studies of unrelated individuals. Several population genetics concepts relevant to understanding genetic epidemiology designs and statistical tools will be introduced including concepts of quantitative and qualitative traits, genetic risk models, allele/haplotype frequency estimation, and migration/admixture. Methods for the evaluation of single and multiple genetic loci in the context of direct and indirect (linkage disequilbrium) associations with human disease will then be addressed, with examples from genome-wide, candidate gene and sequencing approaches. Methods for gene-gene and gene-environment interaction assessment will also be presented. The lecture material will be supplemented with examples using public and simulated data and currently available free software.

Methods of Assessment:

Short Exam and in class polls

Instructor Consent:

No consent required