340.654.81 EPIDEMIOLOGY AND NATURAL HISTORY OF HUMAN VIRAL INFECTIONS

Emphasizes biology, epidemiology, and pathogenesis of diseases caused by human viruses. Discusses virus interaction with host, diagnostic methodologies, immunization, and treatment of viral infections. Examines relationships between viral infections and oncogenesis such as hepatitis/liver cancer, HPV/cervical cancer, EBV/lymphoma, and HTLV/leukemia. Also covers biology and natural history of major viral families such as retroviruses, rabies, and others.

1. Describe the common structures and functions of viruses and their components, including genetics, etc. 2. Identify the main steps of viral pathogenesis 3. Discuss virus-host interactions 4. Recognize the advantages and limiting factors related to antiviral treatment options 5. List several viruses and describe the processes by which they can cause cancer 6. Recall the interaction between viral agents and other factors in the disease pathway 7. Compare the pathogenesis of retroviruses with other viruses, including the mechanisms of invasion and integration and synthesis of new viral particles 8. Recognize and describe the issues of treatment, prevention, and future concerns of human immunodeficiency virus and AIDS 9. Compare and contrast the epidemiology and natural history of other human viral pathogens, including influenza, herpes simplex virus, bovine spongiform encephalitis and others