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Molecular Microbiology and Immunology
2nd term
4 credits
Academic Year:
2014 - 2015
East Baltimore
Class Times:
  • M W F,  1:30 - 2:50pm
Lab Times:
  • M W F,  3:00 - 4:50pm (01)
Auditors Allowed:
Yes, with instructor consent
Grading Restriction:
Letter Grade or Pass/Fail
David Sullivan
Course Instructors:

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Presents a biological basis of parasitic lifestyles including host responses and parasite evasion of host defense mechanisms, transmission, epidemiology, diagnosis, clinical manifestations, pathology, treatment, and control of the major helminthic and protozoan infections of man

Learning Objectives:

Upon successfully completing this course, students will be able to:

  1. Discuss the biological basis for host-parasite adaptation
  2. Define the scope of parasitic infections of global public health importance
  3. Learn epidemiological concepts of relevance to parasite infections
  4. Learn methods of diagnosis, identification and detection of parasites
  5. Learn pathological changes associated with parasite infections
  6. Discuss the role of vectors and intermediate hosts in parasite transmission
  7. Learn the role of vertebrate innate and adaptive immune system in controlling parasites
  8. Learn molecular biology concepts unique to parasite infections
  9. Define the biochemical targets for drugs targeting parasites
  10. Define the mechanisms of drug resistance
  11. Define the immune evasion strategy employed by certain parasites
Methods of Assessment:
Lecture (4 credits): Student evaluation based on a mid-term and a final exam: Midterm 50%, final 50%. Lab (3 credits): midterm practical 30%, final practical 30%, journal club participation 20%, live experiment 20%
Instructor Consent:
No consent required
Special Comments:
Required for MMI students. MMI PhD and ScM should also enroll in 3 credit lab, 260.935. Non-MMI students may take the wet lab with special permission. Laboratory sessions examine living and preserved parasites, gross pathology, histopathology, and vectors. Journal discussions based on research papers and topics of fundamental importance to parasitology will involve student participation in a seminar format.