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260.635.01 BIOLOGY OF PARASITISM

Term: 3rd term
Credits: 4 credits
Contact: David Sullivan
Academic Year: 2012 - 2013
Course Instructors:
Description:

Presents a biological basis of parasitic lifestyles including host responses and parasite evasion of host defense mechanisms, transmission, epidemiology, diagnosis, clinical manifestations, pathology, treatment, and control of the major helminthic and protozoan infections of man

Learning Objective(s):
Upon successfully completing this course, students will be able to:
Discuss the biological basis for host-parasite adaptation
Define the scope of Parasitic Infections of Global Public Health Importance
Learn epidemiological concepts of relevance to parasite infections
Learn methods of diagnosis, identification and detection of parasites
Learn Pathological changes associated with Parasite infections
Discuss the role of vectors and intermediate hosts in parasite transmission
Learn the role of vertebrate innate and adaptive immune system in controlling parasites
Learn molecular biology concepts unique to parasite infections
Define the biochemical targets for drugs targeting parasites
Define the mechanisms of drug resistance
Define the immune evasion strategy employed by certain parasites

Methods of Assessment: Student evaluation based on a mid-term and a final exam.
Location: East Baltimore
Class Times:
  • Monday 8:30 - 9:50
  • Wednesday 8:30 - 9:50
  • Friday 8:30 - 9:50
Lab Times:
  • M W F 10:00 - 11:50 (1)
Enrollment Minimum: 5
Enrollment Maximum: 50
Instructor Consent: No consent required
Auditors Allowed: Yes, with instructor consent
Grading Restriction: Letter Grade or Pass/Fail
Special Comments: Required for MMI students. MMI PhD and ScM should also enroll in 3 credit lab, 260.935. Non-MMI students may take the lab with special permission. Laboratory sessions examine living and preserved parasites, gross pathology, histopathology, and vectors. Journal discussions based on research papers and topics of fundamental importance to parasitology will involve student participation in a seminar format.