260.612.01 PRINCIPLES OF IMMUNOLOGY II

Introduces biological concepts of immunology; molecular nature of antigens; molecular basis for antibody and T-cell receptor structure and diversity; complement; hypersensitivity reactions; cellular basis for the immune response; cell-mediated immunity; adhesion molecules and coreceptors cell activation; cytokines and other soluble mediators; major histocompatibility complex (MHC) antigens; tumor immunology; transplantation immunobiology; mechanisms of resistance to microorganisms; tolerance; autoimmunity; and immuno-deficiency.

• Define the principles of autoimmunity and transplantation • Define the basis underlying primary and acquired immune deficiencies • Define the immune mechanisms employed to combat bacterial, viral and parasitic infections • Define the mechanisms that regulate allergy and hypersensitivity • Define the mechanisms for immunization