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Course Catalog

260.611.01 PRINCIPLES OF IMMUNOLOGY I

Department:
Molecular Microbiology and Immunology
Term:
1st term
Credits:
4 credits
Academic Year:
2013 - 2014
Location:
East Baltimore
Class Times:
  • Tu Th,  8:30 - 10:20am
Grading Restriction:
Letter Grade or Pass/Fail
Course Instructor:

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Prerequisite:

A course in advanced biology

Description:

Introduces biological concepts of immunology; molecular nature of antigens; molecular basis for antibody and T-cell receptor structure and diversity; complement; hypersensitivity reactions; cellular basis for the immune response; cell-mediated immunity; adhesion molecules and coreceptors cell activation; cytokines and other soluble mediators; major histocompatibility complex (MHC) antigens; tumor immunology; transplantation immunobiology; mechanisms of resistance to microorganisms; tolerance; autoimmunity; and immuno-deficiency.

Learning Objectives:

Upon successfully completing this course, students will be able to:

  1. Define the tissue, cellular and molecular components that constitute the vertebrate innate and adaptive immune system
  2. Explain the generation of lymphocyte antigen receptors and the molecular and cellular basis for diversity and specificity of receptors on immune cells
  3. Define the basis for antigen presentation to T cells
  4. Define the basis for recognition of self and non-self recognition
  5. Define the development and survival of lymphocytes
  6. Explain the major signaling pathways used by immune cells
  7. Define T cell-mediated and B cell-mediated immunity
Methods of Assessment:

Student evaluation based on mid-term and final exams.

Instructor Consent:

No consent required

Special Comments:

Required for MMI students.