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Course Catalog

260.611.01 PRINCIPLES OF IMMUNOLOGY I

Term: 1st term
Credits: 4 credits
Academic Year: 2012 - 2013
Course Instructor:
Description:

Introduces biological concepts of immunology; molecular nature of antigens; molecular basis for antibody and T-cell receptor structure and diversity; complement; hypersensitivity reactions; cellular basis for the immune response; cell-mediated immunity; adhesion molecules and coreceptors cell activation; cytokines and other soluble mediators; major histocompatibility complex (MHC) antigens; tumor immunology; transplantation immunobiology; mechanisms of resistance to microorganisms; tolerance; autoimmunity; and immuno-deficiency.

Learning Objective(s):
Upon successfully completing this course, students will be able to:
Define the tissue, cellular and molecular components that constitute the vertebrate innate and adaptive immune system
Explain the generation of lymphocyte antigen receptors and the molecular and cellular basis for diversity and specificity of receptors on immune cells
Define the basis for antigen presentation to T cells
Define the basis for recognition of self and non-self recognition
Define the development and survival of lymphocytes
Explain the major signaling pathways used by immune cells
Define T cell-mediated and B cell-mediated immunity

Methods of Assessment: Student evaluation based on mid-term and final exams.
Location: East Baltimore
Class Times:
  • Tuesday 8:30 - 10:20
  • Thursday 8:30 - 10:20
Enrollment Minimum: 10
Instructor Consent: No consent required
Prerequisite:

A course in advanced biology

Grading Restriction: Letter Grade or Pass/Fail
Special Comments: Required for MMI students.