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Course Catalog



Term: 4th term
Credits: 4 credits
Academic Year: 2014 - 2015
Course Instructor:
  • Xiaofang Yu

Introduces students to the HIV lifecycle and the molecular events occurring during productive infection. Covers topics including the HIV life cycle (Entry, Reverse transcription, Integration, Assembly, Budding, and Maturation), viral regulatory proteins, host innate anti-HIV responses (Apobec and Trim5á), immune responses induced by vaccine and infection, recent progress in HIV vaccine development, origins of HIV, SIV, endogenous retroviruses, new insights in HIV pathogenesis, host factors influencing disease outcome, latency and persistence, transmission, and prophylactic strategies of prevention.

Learning Objective(s):
Upon successfully completing this course, students will be able to:
Define points of the viral lifecycle at which host proteins interfere with viral infection
Understand replication cycle of HIV and contrast with other retroviruses
Assess current vaccine strategies
Analyze current literature
Explain the influence of host factors on disease outcome

Methods of Assessment: Evaluation is based on class participation, core discussion, and a final exam.
Location: East Baltimore
Enrollment Minimum: 10
Instructor Consent: Consent required for all students
For consent, contact:

PH 260.623 or instructor consent

Grading Restriction: Letter Grade or Pass/Fail
Frequency Schedule: