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Course Catalog

260.605.01 GENOMICS


Term: 2nd term
Credits: 4 credits
Contact: Jonathan Pevsner
Academic Year: 2014 - 2015
Course Instructor:

Explores genomes across the tree of life, using the tools of bioinformatics. Topics include viruses; bacteria and archaea; protozoa (e.g. Plasmodium); plants (with a focus on Arabidopsis and rice); the fungi; the metazoans (Drosophila, C. elegans, the rodents, the primates, and human). Each lecture highlights features of the relevant genome(s), key websites and bioinformatics tools, the phylogenetic context in which to understand the significance of the organism, and genomics-based approaches to human disease. Weekly computer labs introduce students to genomics software available on the internet, including tools for genome annotation, comparison, and analysis.

Learning Objective(s):
Upon successfully completing this course, students will be able to:
Define the main features of viral, prokaryotic, and eukaryotic genomes
Define the relevance of various genomes to human disease
Use web-based tools for genome analysis (e.g. annotation and comparison)
Read papers on the sequencing of the human genomes and other genomes, and evaluate the quality and limitations of the analytic approaches

Methods of Assessment: One midterm exam; one final exam; weekly quizzes.
Location: East Baltimore
Class Times:
  • Monday 10:30 - 11:50
  • Wednesday 10:30 - 11:50
  • Friday 10:30 - 11:50
Enrollment Minimum: 10
Enrollment Maximum: 60
Instructor Consent: No consent required
Auditors Allowed: Yes, with instructor consent
Grading Restriction: Letter Grade or Pass/Fail
Jointly Offered With: