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Course Catalog

260.711.01 PRINCIPLES OF NEUROIMMUNOLOGY

Department:
Molecular Microbiology and Immunology
Term:
4th term
Credits:
3 credits
Academic Year:
2014 - 2015
Location:
East Baltimore
Class Times:
  • Tu Th,  9:00 - 10:20am

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Auditors Allowed:
Yes, with instructor consent
Grading Restriction:
Letter Grade or Pass/Fail
Contact:
Monique Stins
Course Instructor:
Frequency Schedule:
Every Other Year
Next Offered:
2018 - 2019
Prerequisite:

Basic knowledge of brain anatomy, physiology and biology.

Description:

Briefly covers the role of specific cells of the central nervous system (CNS), immune functions of CNS cells, and trafficking of leukocytes into the CNS, both in health and disease. Subsequently, it discusses various immune cells, e.g. monocytes, T cells, B cells, inflammatory molecules like cytokines, chemokines, metalloproteinases, and prostaglandins in more detain focusing on their role in either protecting from neurological disease or in causing CNS disease pathologies, including cognitive dysfunction. Presentations from experts in the field address topics such as multiple sclerosis, the role of the Blood Brain Barrier in neurological disease, autism, HIV and other neurotropic microbes.

Learning Objectives:

Upon successfully completing this course, students will be able to:

  1. Explain how the immune system and cellular brain components contribute to neurological disease
  2. Describe the types and effector functions of resident and peripheral immune cells in the human brain, in health and disease
Methods of Assessment:

Course participation and a final exam.

Enrollment Restriction:

Basic knowledge of biology

Instructor Consent:

No consent required