260.711.01
Principles of Neuroimmunology
Location
East Baltimore
Term
4th Term
Department
Molecular Microbiology and Immunology
Credit(s)
3
Academic Year
2014 - 2015
Instruction Method
TBD
Tu, Th, 9:00 - 10:20am
Auditors Allowed
Yes, with instructor consent
Available to Undergraduate
No
Grading Restriction
Letter Grade or Pass/Fail
Course Instructor(s)
Contact Name
Frequency Schedule
Every Other Year
Resources
Prerequisite
Basic knowledge of brain anatomy, physiology and biology.
Briefly covers the role of specific cells of the central nervous system (CNS), immune functions of CNS cells, and trafficking of leukocytes into the CNS, both in health and disease. Subsequently, it discusses various immune cells, e.g. monocytes, T cells, B cells, inflammatory molecules like cytokines, chemokines, metalloproteinases, and prostaglandins in more detain focusing on their role in either protecting from neurological disease or in causing CNS disease pathologies, including cognitive dysfunction. Presentations from experts in the field address topics such as multiple sclerosis, the role of the Blood Brain Barrier in neurological disease, autism, HIV and other neurotropic microbes.
Learning Objectives
Upon successfully completing this course, students will be able to:
- Explain how the immune system and cellular brain components contribute to neurological disease
- Describe the types and effector functions of resident and peripheral immune cells in the human brain, in health and disease
Enrollment Restriction
Basic knowledge of biology