340.734.01
Principles of Genetic Epidemiology 4
Location
East Baltimore
Term
4th Term
Department
Epidemiology
Credit(s)
2
Academic Year
2013 - 2014
Instruction Method
TBD
Thursday, 1:30 - 3:20pm
Auditors Allowed
Yes, with instructor consent
Available to Undergraduate
No
Grading Restriction
Letter Grade or Pass/Fail
Course Instructor(s)
Course Instructor(s)
Robert Wojciechowski
Contact Name
Frequency Schedule
Every Year
Resources
Prerequisite
340.733; 340.753, 140.623 or 140.653; or instructor consent
Discusses advanced topics in genetic epidemiology methods. Builds on the knowledge gained in Principles of Genetic Epidemiology 1-3. Students discuss the details of the methods they have learned, and are also exposed to cutting-edge topics not yet in the mainstream. Also covers emerging topics such as CNV analysis, epigenetic analysis, sequencing analysis, and admixture mapping. Students also carry out an independent analysis project through the term.
Learning Objectives
Upon successfully completing this course, students will be able to:
- Evaluate the various approaches to gene-gene and gene-environment interaction, and enrichment analyses such as gene set analysis and pathway analysis
- Use public databases and bioinformatics approaches to data mining and annotation
- Evaluate the use of endophenotypes, extreme sampling, and other strategies to maximize the use of existing data
- Evaluate and compare design choices, laboratory methods, and statistical approaches for sequencing studies