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223.690.01
The Design and Analysis of Cluster Randomized Trials

Location
East Baltimore
Term
4th Term
Department
International Health
Credit(s)
2
Academic Year
2012 - 2013
Instruction Method
TBD
Class Time(s)
Tuesday, 3:30 - 5:20pm
Auditors Allowed
Yes, with instructor consent
Available to Undergraduate
No
Grading Restriction
Letter Grade or Pass/Fail
Course Instructor(s)
Contact Name
Frequency Schedule
Every Year
Prerequisite

Biostatistics 621, 622, 623, 624 or equivalent sequence.

Description
Covers the major concepts and methods in the design and analysis of trial in which the unit of randomization is a group of participants. Focuses on design: discusses unmatched, matched, stepped wedge, and other approaches, with particular attention paid to randomization and sample size considerations. Presents a variety of methods for the analysis of these correlated-outcomes studies. Includes special aspects of infectious disease interventions.
Learning Objectives
Upon successfully completing this course, students will be able to:
  1. Identify when a cluster randomized trial may be preferable to an individually randomized trial.
  2. Determine optimal design strategies for enabling estimation of efficacy and effectiveness parameters of interest.
  3. Conduct and interpret statistical analyses appropriate to these designs.